31 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ednrbs-36Pub/Ednrb+ Spry2tm1.1Mrt/Spry2+ involves: 101/Rl * 129P2/OlaHsd * C3H/Rl * C57BL/6J	abnormal palatal rugae morphology	J:125229
	cleft secondary palate	J:125229
Ednrbs-36Pub/Ednrbs-36Pub Tg(Spry2)2Tpo/0 B6.Cg-Ednrbs-36Pub Tg(Spry2)2Tpo	abnormal palate bone morphology	J:125229
	cleft secondary palate	J:125229
	normal craniofacial phenotype	J:125229
	maxillary shelf hypoplasia	J:125229
Ednrbs-36Pub/Ednrbs-36Pub Tg(Spry2)69Tpo/0 B6.Cg-Ednrbs-36Pub Tg(Spry2)69Tpo	abnormal palate bone morphology	J:125229
	cleft secondary palate	J:125229
	normal craniofacial phenotype	J:125229
	maxillary shelf hypoplasia	J:125229
Fgfr1tm1.1Jpa/Fgfr1+ Spry2tm1.1Mrt/Spry2tm1.1Mrt involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	supernumerary teeth	J:119280
Fgfr2tm1.1Dor/Fgfr2+ Spry2tm1.1Mrt/Spry2tm1.1Mrt involves: 129P2/OlaHsd * 129X1/SvJ	normal craniofacial phenotype	J:119280
Krastm4.1Tyj/Kras+ Spry2tm1Mrt/Spry2tm1Mrt involves: 129P2/OlaHsd	increased lung tumor incidence	J:119477
Krastm4Tyj/Kras+ Spry2tm1.1Mrt/Spry2tm1.1Mrt Meox2tm1(cre)Sor/Meox2+ involves: 129P2/OlaHsd * 129S4/SvJaeSor * FVB/N	impaired branching involved in bronchus morphogenesis	J:119477
Ptentm2.1Ppp/Pten+ Spry1tm1Jdli/Spry1tm1.1Jdli Spry2tm1Mrt/Spry2tm1.1Mrt Tg(Osr1-cre)4Mrt/0 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N	increased prostate gland tumor incidence	J:192348
	increased prostate intraepithelial neoplasia incidence	J:192348
Ptentm2.1Ppp/Ptentm2.1Ppp Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0 Tg(Osr1-cre)4Mrt/0 involves: 129P2/OlaHsd * 129S1/Sv * FVB/N	increased prostate intraepithelial neoplasia incidence	J:192348
Spry1tm1Jdli/Spry1tm1.1Jdli Spry2tm1Mrt/Spry2tm1.1Mrt Tg(Osr1-cre)4Mrt/0 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N	increased prostate intraepithelial neoplasia incidence	J:192348
	prostate gland epithelial hyperplasia	J:192348
Spry2tm1.1Mrt/Spry2+ Spry4tm1.2Mrt/Spry4tm1.2Mrt involves: 129P2/OlaHsd	abnormal autopod morphology	J:315670
	abnormal chondrocyte morphology	J:315670
	abnormal primary cilium morphology	J:315670
	abnormal skeleton morphology	J:315670
	increased enchondroma incidence	J:315670
	increased osteochondroma incidence	J:315670
	short tibia	J:315670
Spry2tm1.1Mrt/Spry2tm1.1Mrt Spry4tm1.2Mrt/Spry4+ involves: 129P2/OlaHsd	abnormal autopod morphology	J:315670
	abnormal skeleton morphology	J:315670
	increased enchondroma incidence	J:315670
	increased osteochondroma incidence	J:315670
Spry2tm1Ayos/Spry2+ Spry4tm1Ayos/Spry4tm1Ayos involves: 129 * C57BL/6J	decreased body weight	J:116506
	perinatal lethality, incomplete penetrance	J:116506
	postnatal lethality, incomplete penetrance	J:116506
Spry2tm1Ayos/Spry2tm1Ayos Spry4tm1Ayos/Spry4+ involves: 129 * C57BL/6J	prenatal lethality, complete penetrance	J:116506
Spry2tm1Ayos/Spry2tm1Ayos Spry4tm1Ayos/Spry4tm1Ayos involves: 129 * C57BL/6J	abnormal brain development	J:116506
	abnormal craniofacial morphology	J:116506
	abnormal forebrain development	J:116506
	abnormal limb morphology	J:116506
	abnormal lung development	J:116506
	abnormal respiratory conducting tube morphology	J:116506
	alobar holoprosencephaly	J:116506
	cyclopia	J:116506
	embryonic lethality during organogenesis, incomplete penetrance	J:116506
	prenatal lethality, complete penetrance	J:116506