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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Eomes
eomesodermin
MGI:1201683
37 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Eomestm1.1Bflu/Eomestm1.1Bflu
Tbx21tm1Glm/Tbx21tm1Glm
Tg(Cd4-cre)1Cwi/0
involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * SJL
abnormal leukocyte migration J:163822
decreased CD4-positive, alpha beta T cell number J:163822
decreased CD8-positive, alpha-beta T cell number J:163822
decreased interferon-gamma secretion J:163822
decreased memory T cell number J:163822
increased interleukin-4 secretion J:163822
increased interleukin-17 secretion J:163822
increased tumor incidence J:163822
Eomestm1.1Rob/Eomes+
Wnt3tm1Brd/Wnt3+
involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * CBA
no abnormal phenotype detected J:131055
Eomestm1.1Rob/Eomes+
Nodaltm1Rob/Nodal+
involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * CBA
abnormal amniotic cavity morphology J:131055
abnormal anterior visceral endoderm cell migration J:131055
abnormal developmental patterning J:131055
abnormal germ layer development J:131055
abnormal left-right axis patterning J:131055
abnormal notochord morphology J:131055
abnormal primitive node morphology J:131055
abnormal rostral-caudal patterning of the somites J:131055
disorganized embryonic tissue J:131055
embryonic-extraembryonic boundary constriction J:131055
enlarged floor plate J:131055
failure of primitive streak formation J:131055
increased somite number J:131055
rostral body truncation J:131055
rostral-caudal axis duplication J:131055
Eomestm1.1Rob/Eomes+
Nodaltm4Rob/Nodaltm4Rob
involves: 129S/SvEv * C57BL/6 * CBA
no abnormal phenotype detected J:131055
Eomestm1.1Twa/?
Il15tm1Imx/Il15tm1Imx
involves: C57BL/6 * C57BL/6N
abnormal NK cell differentiation J:210160
Eomestm1.1Twa/?
Tbx21tm1Glm/Tbx21tm1Glm
involves: 129S6/SvEvTac * C57BL/6N
abnormal NK cell differentiation J:210160
Eomestm1.1Twa/?
Tg(CD2-Tbx21)#Staka/?
involves: C57BL/6N
abnormal NK cell differentiation J:210160
Eomestm1.1Twa/?
Tg(Itgax-TGFBR2)1Flv/?
involves: C3H * C57BL/6 * C57BL/6N
abnormal NK cell differentiation J:210160
Eomestm1Apr/Eomes+
Tbx21tm1Srnr/Tbx21tm1Srnr
involves: C57BL/6
decreased interferon-gamma secretion J:112679
decreased memory T cell number J:112679
decreased NK cell number J:112679
decreased NK T cell number J:112679
Eomestm1Rob/Eomes+
Nodaltm1Rob/Nodal+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/SvEv * C57BL/6 * CBA
prenatal lethality J:131055
rostral body truncation J:131055
Eomestm1Rob/Eomestm1.1Rob
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA
abnormal endoderm development J:131055
abnormal visceral endoderm morphology J:131055
Eomestm1Srnr/Eomestm1Srnr
Tbx21tm1Srnr/Tbx21tm1Srnr
Tg(Cd4-cre)1Cwi/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
abnormal CD8-positive, alpha-beta T cell differentiation J:137655
abnormal immune system physiology J:137655
abnormal interleukin level J:137655
abnormal leukocyte physiology J:137655
abnormal T cell morphology J:137655
decreased CD8-positive, alpha-beta T cell number J:137655
decreased memory T cell number J:137655
increased neutrophil cell number J:137655
increased susceptibility to viral infection J:137655

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory