About   Help   FAQ
Due to maintenance, access to MGI may be intermittent 8:00 AM ET Wed, September 18.
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Nrxn2
neurexin II
MGI:1096362
16 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Nrxn1tm1Sud/Nrxn1tm1Sud
Nrxn2tm1Sud/Nrxn2tm1Sud
involves: 129 * C57BL/6
abnormal CNS synaptic transmission J:89452
abnormal excitatory postsynaptic currents J:89452
decreased CNS synapse formation J:89452
postnatal lethality, incomplete penetrance J:89452
respiratory distress J:89452
Nrxn1tm1Sud/Nrxn1tm1Sud
Nrxn2tm1Sud/Nrxn2tm1Sud
Nrxn3tm1Sud/Nrxn3tm1Sud
involves: 129 * C57BL/6
abnormal CNS synaptic transmission J:88641, J:89452
abnormal GABA-mediated receptor currents J:89452
abnormal paired-pulse inhibition J:89452
abnormal synaptic depression J:89452
decreased CNS synapse formation J:89452
decreased excitatory postsynaptic current amplitude J:89452
decreased neurotransmitter release J:89452
neonatal lethality, complete penetrance J:89452
reduced AMPA-mediated synaptic currents J:89452
reduced NMDA-mediated synaptic currents J:88641
respiratory distress J:89452
Nrxn1tm2Sud/Nrxn1tm2Sud
Nrxn2tm2Sud/Nrxn2tm2Sud
Nrxn3tm2Sud/Nrxn3tm2Sud
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
no abnormal phenotype detected J:101977
Nrxn2tm1Sud/Nrxn2tm1Sud
Nrxn3tm1Sud/Nrxn3tm1Sud
involves: 129 * C57BL/6
abnormal breathing pattern J:89452
abnormal excitatory postsynaptic currents J:89452
postnatal lethality, incomplete penetrance J:89452
premature death J:89452

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/10/2019
MGI 6.14
The Jackson Laboratory