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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Rgs4
regulator of G-protein signaling 4
MGI:108409
27 phenotypes from 6 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Rgs4em1(IMPC)H/Rgs4em1(IMPC)H
C57BL/6N-Rgs4em1(IMPC)H/H
decreased circulating total protein level J:211773
decreased lymphocyte cell number J:211773
increased eosinophil cell number J:211773
increased mean corpuscular volume J:211773
increased spleen weight J:211773
Rgs4tm1.1Amus/Rgs4tm1.1Amus
B6.129-Rgs4tm1.1Amus
decreased renal plasma flow rate J:195186
increased susceptibility to xenobiotic induced morbidity/mortality J:195186
Rgs4tm1.1Jbr/Rgs4tm1.1Jbr
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
abnormal touch/ nociception J:98888
decreased behavioral withdrawal response J:98888
decreased body weight J:98888
embryonic lethality between somite formation and embryo turning, incomplete penetrance J:98888
impaired behavioral response to morphine J:98888
impaired coordination J:98888
normal nervous system phenotype J:98888
Rgs4tm1.1Jlr/Rgs4tm1.1Jlr
involves: 129S1/SvImJ * 129S4/SvJae * 129S6/SvEvTac
no abnormal phenotype detected J:160728
Rgs4tm1Dgen/Rgs4tm1Dgen
B6.129P2-Rgs4tm1Dgen
normal behavior/neurological phenotype J:171292
decreased aggression towards mice J:171292
hyperactivity J:171292
impaired conditioned place preference behavior J:171292
increased vertical activity J:171292
Rgs4tm1Dgen/Rgs4tm1Dgen
involves: 129P2/OlaHsd * C57BL/6
increased circulating cholesterol level J:101679
increased circulating HDL cholesterol level J:101679
increased total body fat amount J:101679
Rgs4tm1Sdlk/Rgs4tm1Sdlk
Tg(Myh11-icre/ERT2)1Soff/?
involves: FVB/N
abnormal macrophage chemotaxis J:215588
abnormal renal tubule morphology J:215588
increased circulating creatinine level J:215588
increased susceptibility to induced morbidity/mortality J:215588

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory