Sfrp2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sfrp2
secreted frizzled-related protein 2
MGI:108078

23 phenotypes from 6 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sfrp2^C50F/Sfrp2^C50F involves: BALB/c * C3H/HeH	normal reproductive system phenotype	J:119228
Sfrp2^tm1.1Brle/Sfrp2^tm1.1Brle B6;129-Sfrp2^tm1.1Brle/J	normal reproductive system phenotype	J:275639
Sfrp2^tm1.1Brle/Sfrp2^tm1.1Brle involves: 129S7/SvEvBrd	syndactyly	J:186306
Sfrp2^tm1.1Brle/Sfrp2^tm1.1Brle involves: 129S7/SvEvBrd * C57BL/6	abnormal chondrocyte physiology	J:186306
	abnormal long bone diaphysis morphology	J:186306
	brachydactyly	J:186306
	brachypodia	J:186306
	decreased length of long bones	J:186306
	delayed endochondral bone ossification	J:186306
	short metacarpal bones	J:186306
	short metatarsal bones	J:186306
	short radius	J:186306
	short ulna	J:186306
	syndactyly	J:186306
Sfrp2^tm1Aksh/Sfrp2^tm1Aksh involves: 129 * C57BL/6	syndactyly	J:106551
Sfrp2^tm1Ktas/Sfrp2⁺ involves: 129X1/SvJ	syndactyly	J:138805
Sfrp2^tm1Ktas/Sfrp2⁺ involves: 129X1/SvJ * C57BL/6	normal limbs/digits/tail phenotype	J:138805
Sfrp2^tm1Ktas/Sfrp2⁺ involves: 129X1/SvJ * CBA/N	syndactyly	J:138805
Sfrp2^tm1Ktas/Sfrp2^tm1Ktas involves: 129X1/SvJ	abnormal caudal vertebrae morphology	J:138805
	abnormal digit development	J:138805
	abnormal interdigital cell death	J:138805
	abnormal vertebral epiphyseal plate morphology	J:138805
	kinked tail	J:138805
	syndactyly	J:138805
Sfrp2^tm1Ktas/Sfrp2^tm1Ktas involves: 129X1/SvJ * C57BL/6	abnormal caudal vertebrae morphology	J:138805
	abnormal digit development	J:138805
	abnormal interdigital cell death	J:138805
	abnormal vertebral epiphyseal plate morphology	J:138805
	kinked tail	J:138805
	polysyndactyly	J:138805
	syndactyly	J:138805
Sfrp2^tm1Ktas/Sfrp2^tm1Ktas involves: 129X1/SvJ * CBA/N	abnormal caudal vertebrae morphology	J:138805
	abnormal digit development	J:138805
	abnormal interdigital cell death	J:138805
	abnormal vertebral epiphyseal plate morphology	J:138805
	kinked tail	J:138805
	syndactyly	J:138805
Sfrp2^tm1Nat/Sfrp2^tm1Nat involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:137889
Sfrp2^tm1Sato/Sfrp2^tm1Sato Not Specified	abnormal neuron differentiation	J:112802
	abnormal response of heart to induced stress	J:146963
	increased cardiac muscle contractility	J:146963

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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