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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hrh1
histamine receptor H1
MGI:107619
38 phenotypes from 4 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Hrh1Bphs-r/Hrh1Bphs-r
C3H/HeJ
normal immune system phenotype J:4933, J:77938
Hrh1Bphs-r/Hrh1Bphs-s
(C3H/HeJ x SJL/J)F1
abnormal immune system physiology J:77938
abnormal response to infection J:77938
increased susceptibility to bacterial infection J:77938
increased susceptibility to bacterial infection induced morbidity/mortality J:77938
Hrh1Bphs-s/Hrh1Bphs-s
C3.SJL-Hrh1Bphs-s
abnormal response to infection J:77938
increased susceptibility to bacterial infection J:77938
increased susceptibility to bacterial infection induced morbidity/mortality J:77938
Hrh1em1(IMPC)Rbrc/Hrh1em1(IMPC)Rbrc
Not Specified
abnormal kidney morphology J:211773
Hrh1tm1Wtn/Hrh1tm1Wtn
B6.129P2-Hrh1tm1Wtn
abnormal circadian feeding behavior J:107191
abnormal response/metabolism to endogenous compounds J:107191
decreased body weight J:107191
decreased circulating insulin level J:107191
decreased food intake J:107191
decreased inflammatory response J:110367
decreased interferon-gamma secretion J:110367
decreased interleukin-5 secretion J:110367
decreased interleukin-13 secretion J:110367
decreased total body fat amount J:107191
increased body weight J:107191
increased brown adipose tissue amount J:107191
increased circulating free fatty acid level J:107191
increased circulating leptin level J:107191
increased fat cell size J:107191
increased food intake J:107191
increased IgG level J:110367
increased IgM level J:110367
increased liver triglyceride level J:107191
increased triglyceride level J:107191
increased white adipose tissue amount J:107191
Hrh1tm1Wtn/Hrh1tm1Wtn
involves: 129P2/OlaHsd * C57BL/6
abnormal behavior J:36556
abnormal locomotor circadian rhythm J:36556
decreased B cell proliferation J:111704
decreased exploration in new environment J:36556
decreased IgG3 level J:111704
decreased IgM level J:111704
decreased interferon-gamma secretion J:111704
decreased interleukin-2 secretion J:111704
decreased T cell number J:111704
decreased T cell proliferation J:111704
decreased vertical activity J:36556
increased interleukin-4 secretion J:111704

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory