Srebf2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Srebf2
sterol regulatory element binding factor 2
MGI:107585

15 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Srebf2^{Gt(YTA054)Byg}/Srebf2^{Gt(YTA054)Byg} involves: 129P2/OlaHsd * C57BL/6J	prenatal lethality, complete penetrance	J:176249
Srebf2^{Gt(YTA054)Byg}/Srebf2^lop13 involves: 129P2/OlaHsd * 129T1/Sv * C57BL/6J	abnormal lens fiber morphology	J:176249
	abnormal skin condition	J:176249
	cataract	J:176249
	prenatal lethality, incomplete penetrance	J:176249
Srebf2^lop13/Srebf2^lop13 STOCK Srebf2^lop13/J	abnormal lens fiber morphology	J:176249
	abnormal skin condition	J:176249
	cataract	J:13874, J:176249
	decreased brain cholesterol level	J:176249
	decreased cholesterol level	J:176249
	decreased liver cholesterol level	J:176249
	nuclear cataract	J:176249
	normal vision/eye phenotype	J:13874
Srebf2^tm1Jdh/Srebf2^tm1Jdh Speer6-ps1^{Tg(Alb-cre)21Mgn}/? involves: 129S6/SvEvTac * C57BL/6 * DBA	abnormal lipid homeostasis	J:241873
	decreased body weight	J:241873
	decreased circulating cholesterol level	J:241873
	decreased circulating triglyceride level	J:241873
	decreased liver cholesterol level	J:241873
	decreased liver triglyceride level	J:241873

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23