About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Il17a
interleukin 17A
MGI:107364
42 phenotypes from 6 alleles in 9 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Gt(ROSA)26Sortm3(CAG-Il17a)Awai/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0
involves: C57BL/6 * DBA/2
abnormal immune system physiology J:144710
abnormal neutrophil physiology J:144710
increased circulating interleukin-17 level J:144710
increased granulocyte number J:144710
increased interleukin-17 secretion J:144710
Gt(ROSA)26Sortm3.1(CAG-Il17a)Awai/Gt(ROSA)26Sor+
involves: BALB/c * C57BL/6
anemia J:144710
decreased hematocrit J:144710
decreased hemoglobin content J:144710
decreased mean corpuscular hemoglobin J:144710
decreased mean corpuscular volume J:144710
increased granulocyte number J:144710
increased interleukin-17 secretion J:144710
postnatal growth retardation J:144710
skin inflammation J:144710
Il17a/Il17ftm1.1Impr/Il17a/Il17ftm1.1Impr
involves: C57BL/6
abnormal effector T cell morphology J:187400
absent gamma-delta T cells J:187400
decreased interleukin-17 secretion J:187400
normal immune system phenotype J:187400, J:189794
increased gamma-delta T cell number J:187400
increased T cell proliferation J:187400
Il17atm1Cdon/Il17atm1Cdon
involves: C57BL/6
chronic inflammation J:136279
decreased CD4-positive, alpha beta T cell number J:136279
decreased IgG1 level J:136279
decreased IgG2a level J:136279
decreased IgG2b level J:136279
decreased IgM level J:136279
decreased interleukin-17 secretion J:136279
decreased susceptibility to experimental autoimmune encephalomyelitis J:136279
increased susceptibility to induced colitis J:136279
Il17atm1Yiw/Il17atm1Yiw
B6.129P2-Il17atm1Yiw
increased susceptibility to infection induced morbidity/mortality J:160680
Il17atm1Yiw/Il17atm1Yiw
involves: 129P2/OlaHsd
abnormal immune system physiology J:144710
decreased neutrophil cell number J:193548
decreased physiological sensitivity to xenobiotic J:193548
increased gamma-delta T cell number J:193548
Il17atm1Yiw/Il17atm1Yiw
involves: 129P2/OlaHsd * BALB/cA * C57BL/6J
abnormal interleukin level J:79127
abnormal Langerhans cell physiology J:79127
decreased IgE level J:79127
decreased IgG1 level J:79127
decreased immunoglobulin level J:79127
decreased susceptibility to type IV hypersensitivity reaction J:79127
Il17atm1Yiw/Il17atm1Yiw
involves: 129P2/OlaHsd * C57BL/6
increased susceptibility to bacterial infection J:143719
Il17atm1Yiw/Il17atm1Yiw
involves: 129P2/OlaHsd * C57BL/6J
decreased IgG level J:79127
decreased immunoglobulin level J:79127
decreased interferon-gamma secretion J:79127
decreased susceptibility to type IV hypersensitivity reaction J:79127
Tg(Scgb1a1-Il17a)3Cdon/0
C57BL/6-Tg(Scgb1a1-Il17a)3Cdon
abnormal bronchiole morphology J:112600
abnormal chemokine level J:112600
abnormal lung epithelium morphology J:112600
lung inflammation J:112600
thick pulmonary interalveolar septum J:112600

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/10/2017
MGI 6.10
The Jackson Laboratory