111 phenotypes from 9 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lama5b2b2966.1Clo/Lama5b2b2966.1Clo C57BL/6J-Lama5b2b2966.1Clo	abnormal autopod morphology	J:175213
	abnormal pulmonary artery morphology	J:175213
	abnormal right subclavian artery morphology	J:175213
	abnormal thoracic cavity morphology	J:175213
	absent kidney	J:175213
	anophthalmia	J:175213
	atrioventricular septal defect	J:175213
	curly tail	J:175213
	decreased body size	J:175213
	dilated renal tubule	J:175213
	double outlet right ventricle	J:175213
	exencephaly	J:175213
	interrupted aortic arch	J:175213
	kidney cyst	J:175213
	left pulmonary isomerism	J:175213
	lowered ear position	J:175213
	mesocardia	J:175213
	microphthalmia	J:175213
	persistent truncus arteriosus	J:175213
	pulmonary artery hypoplasia	J:175213
	right aortic arch	J:175213
	syndactyly	J:175213
	thymus hypoplasia	J:175213
	vascular ring	J:175213
	ventricular septal defect	J:175213
Lama5Gt1Jhm/Lama5+ Not Specified	abnormal tooth development	J:108325
Lama5Gt1Jhm/Lama5Gt1Jhm Not Specified	abnormal brain development	J:108325
	abnormal digit morphology	J:108325
	abnormal embryo size	J:108325
	abnormal extraembryonic tissue morphology	J:108325
	abnormal head morphology	J:108325
	abnormal limb morphology	J:108325
	abnormal lung morphology	J:108325
	abnormal nervous system morphology	J:108325
	lethality throughout fetal growth and development, complete penetrance	J:108325
Lama5mpc205H/Lama5mpc205H involves: BALB/c * C3H/HeH * C57BL/6J	increased blood urea nitrogen level	J:234901
	increased circulating creatinine level	J:234901
Lama5tm1.1Mggte/Lama5tm1.1Mggte involves: 129P2/OlaHsd	abnormal epidermal-dermal junction morphology	J:286800
	abnormal hair follicle dermal papilla morphology	J:286800
	abnormal hair follicle development	J:286800
	abnormal intestinal mucosa morphology	J:286800
	abnormal small intestinal villus morphology	J:286800
	clubbed small intestinal villi	J:286800
	decreased hair follicle number	J:286800
Lama5tm1b(KOMP)Wtsi/Lama5+ C57BL/6N-Lama5tm1b(KOMP)Wtsi/H	enlarged heart	J:211773
Lama5tm1b(KOMP)Wtsi/Lama5tm1b(KOMP)Wtsi C57BL/6N-Lama5tm1b(KOMP)Wtsi/H	preweaning lethality, complete penetrance	J:211773
Lama5tm1Jhm/Lama5+ involves: 129S1/Sv * 129X1/SvJ	abnormal tooth development	J:108325
Lama5tm1Jhm/Lama5tm1Jhm involves: 129 * C57BL/6J	abnormal glomerular capillary endothelium morphology	J:59925
	abnormal glomerular capillary morphology	J:59925
	abnormal intestinal epithelium morphology	J:84903
	abnormal intestinal goblet cell morphology	J:84903
	abnormal intestine morphology	J:84903
	abnormal kidney development	J:59925
	abnormal limb morphology	J:51557
	abnormal mesangial cell morphology	J:59925
	abnormal placenta morphology	J:51557
	abnormal placental labyrinth vasculature morphology	J:51557
	abnormal podocyte morphology	J:59925
	abnormal right lung morphology	J:77264
	abnormal trophoblast layer morphology	J:51557
	abnormal visceral pleura morphology	J:77264
	absent kidney	J:59925
	absent neurocranium	J:51557
	absent ureter	J:59925
	decreased fetal size	J:51557
	decreased placental labyrinth size	J:51557
	exencephaly	J:51557
	impaired basement membrane formation	J:77264
	impaired branching involved in ureteric bud morphogenesis	J:84903
	incomplete rostral neuropore closure	J:51557
	lethality throughout fetal growth and development, complete penetrance	J:51557
	megacephaly	J:51557
	small kidney	J:59925
	small lung	J:77264
	syndactyly	J:51557
Lama5tm1Jhm/Lama5tm2Jhm Tg(SFTPC-rtTA)5Jaw/? Tg(tetO-cre)1Jaw/? involves: 129S1/Sv * 129X1/SvJ	abnormal lung development	J:104565
	abnormal lung vasculature morphology	J:104565
	abnormal pulmonary alveolus epithelium morphology	J:104565
	abnormal pulmonary alveolus morphology	J:104565
	absent type I pneumocytes	J:104565
	cyanosis	J:104565
	decreased cell proliferation	J:104565
	decreased type II pneumocyte number	J:104565
	increased apoptosis	J:104565
	neonatal lethality, complete penetrance	J:104565
	overexpanded pulmonary alveolus	J:104565
	pulmonary hypoplasia	J:104565
	respiratory distress	J:104565
	respiratory failure	J:104565
	thin lung-associated mesenchyme	J:104565
Lama5tm1Lsor/Lama5tm1Lsor Tg(Tek-cre)1Ywa/0 involves: C57BL/6 * SJL	abnormal marginal zone B cell physiology	J:198783
	decreased marginal zone B cell number	J:198783
	decreased transitional stage T2 B cell number	J:198783
	increased B cell number	J:198783
	increased IgM level	J:198783
	increased transitional stage T1 B cell number	J:198783
Lama5tm2Jhm/Lama5tm1Jhm Tg(NPHS2-cre)295Lbh/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL	abnormal kidney morphology	J:185850
	abnormal renal glomerulus basement membrane morphology	J:185850
	decreased circulating serum albumin level	J:185850
	edema	J:185850
	expanded mesangial matrix	J:185850
	glomerulosclerosis	J:185850
	hematuria	J:185850
	increased circulating cholesterol level	J:185850
	increased renal glomerulus basement membrane thickness	J:185850
	increased urine protein level	J:185850
	podocyte foot process effacement	J:185850
	tubulointerstitial nephritis	J:185850
Lama5tm2Jhm/Lama5tm2Jhm Tg(ACTA1-cre)1Mll/0 involves: 129S1/Sv * 129X1/SvJ	abnormal neuromuscular synapse morphology	J:142595
Lama5tm2Jhm/Lama5tm2Jhm Tg(NPHS2-cre)295Lbh/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL	postnatal lethality, incomplete penetrance	J:185850
Lama5tm3Jhm/Lama5tm3Jhm involves: 129S1/Sv * 129X1/SvJ	abnormal renal glomerulus basement membrane morphology	J:128225
	decreased body size	J:128225
	dilated renal tubule	J:128225
	enlarged kidney	J:128225
	increased blood urea nitrogen level	J:128225
	increased kidney apoptosis	J:128225
	increased urine protein level	J:128225
	kidney failure	J:128225
	polycystic kidney	J:128225
	premature death	J:128225
	renal interstitial fibrosis	J:128225
Lama5tm3Jhm/Lama5tm3Jhm involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	hematuria	J:185850
	increased urine protein level	J:185850
	polycystic kidney	J:185850
	premature death	J:185850
Lama5tm3Jhm/Lama5tm3Jhm Tg(Nphs1-flpo)1Jhm/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	normal renal/urinary system phenotype	J:185850