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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hes3
hes family bHLH transcription factor 3
MGI:104877
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Emx1tm1(cre)Ito/Emx1+
Hes1tm1Kag/Hes1tm1Kag
Hes3tm1Kag/Hes3tm1Kag
Hes5tm1Fgu/Hes5tm1Fgu
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal brain morphology J:139170
abnormal embryonic neuroepithelium morphology J:139170
abnormal neuron differentiation J:139170
absent choroid plexus J:139170
increased Cajal-Retzius cell number J:139170
Hes1tm1Fgu/Hes1tm1Fgu
Hes3tm1Kag/Hes3tm1Kag
involves: C57BL/6 * CBA * ICR 		abnormal brain development J:71074
abnormal dopaminergic neuron morphology J:71074
abnormal locus ceruleus morphology J:71074
abnormal midbrain morphology J:71074
abnormal midbrain-hindbrain boundary morphology J:71074
abnormal neural tube morphology J:71074
abnormal oculomotor nucleus morphology J:71074
absent oculomotor nerve J:71074
absent trochlear nerve J:71074
embryonic growth retardation J:71074
exencephaly J:71074
lethality throughout fetal growth and development, complete penetrance J:71074
premature neuronal precursor differentiation J:71074
Hes1tm1Fgu/Hes1tm1Fgu
Hes3tm1Kag/Hes3tm1Kag
Hes5tm1Fgu/Hes5tm1Fgu
involves: 129S1/Sv * 129X1/SvJ * CD-1 		premature neuronal precursor differentiation J:94391
Hes1tm1Kag/Hes1tm1Kag
Hes3tm1Kag/Hes3tm1Kag
Hes5tm1Fgu/Hes5tm1Fgu
Tg(Nes-cre/ERT2)5-1Imayo/0
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		normal nervous system phenotype J:139170
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory