Tg(Nes-cre/ERT2)5-1Kag
Transgene Detail

Summary

• Symbol: Tg(Nes-cre/ERT2)5-1Kag
• Name: transgene insertion 5-1, Ryoichiro Kageyama
• MGI ID: MGI:3641212
• Synonyms: Nes-CreER^T2, Nestin-CreER.line5
• Transgene: Tg(Nes-cre/ERT2)5-1Kag Location: unknown
• Alliance: Tg(Nes-cre/ERT2)5-1Kag page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Nes-cre/ERT2)5-1Kag expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Nes (25491)

  Nes	(MGI:101784)

• Mutation details: This transgene consists of a 5.8 kb fragment of the rat Nes promoter and a 1.8 kb fragment of the second intron of Nes driving expression of a tamoxifen-inducible form of cre recombinase followed by an SV40 poly A sequence. This line show tamoxifen-inducible Cre activity in the developing nervous system and no Cre activity in the absence of tamoxifen. (J:110145)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nes (rat) Summary of all recombinase alleles driven by Nes. Comparative matrix view of recombinase activities Alliance rat Nes gene page

Tumor Data

List all tumor models in MMHCdb carrying Tg(Nes-cre/ERT2)5-1Kag

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:110145 Imayoshi I, et al., Temporal regulation of Cre recombinase activity in neural stem cells. Genesis. 2006 May;44(5):233-8
• All: 24 reference(s)