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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Alk
anaplastic lymphoma kinase
MGI:103305
42 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Alktm1.1Ics/?
involves: 129S2/SvPas * C57BL/6
abnormal stellate ganglion morphology J:228124
enlarged superior cervical ganglion J:228124
Alktm1.1Rhp/Alktm1.1Rhp
involves: 129 * C57BL/6N
abnormal hypothalamus morphology J:226955
abnormal hypothalamus secretion J:226955
abnormal male germ cell morphology J:226955
abnormal seminiferous tubule morphology J:226955
abnormal sperm number J:226955
decreased body weight J:226955
decreased circulating testosterone level J:226955
decreased Sertoli cell number J:226955
decreased testis weight J:226955
delayed balanopreputial separation J:226955
delayed male fertility J:226955
delayed sexual maturation J:226955
increased testis apoptosis J:226955
normal reproductive system phenotype J:226955
slow postnatal weight gain J:226955
small testis J:226955
Alktm1Swm/Alktm1Swm
involves: 129P2/OlaHsd * C57BL/6J
normal behavior/neurological phenotype J:227538
enhanced behavioral response to alcohol J:227538
normal homeostasis/metabolism phenotype J:227538
increased alcohol consumption J:227538
Alktm2.1Ics/Alk+
B6N.129S2(Cg)-Alktm2.1Ics
abnormal behavior J:226655
abnormal eye morphology J:226655
decreased food intake J:226655
decreased locomotor activity J:226655
decreased vertical activity J:226655
increased anxiety-related response J:226655
increased circulating alkaline phosphatase level J:226655
increased circulating chloride level J:226655
increased grip strength J:226655
Alktm2.1Ics/Alk+
involves: 129S2/SvPas * C57BL/6
abnormal stellate ganglion morphology J:228124
abnormal superior cervical ganglion morphology J:228124
abnormal sympathetic ganglion morphology J:228124
enlarged superior cervical ganglion J:228124
Alktm2.1Ics/Alktm2.1Ics
B6N.129S2(Cg)-Alktm2.1Ics
abnormal behavior J:226655
abnormal long bone diaphysis morphology J:226655
apnea J:226655
decreased body size J:226655
decreased body weight J:226655
decreased food intake J:226655
delayed hair appearance J:226655
delayed skin pigmentation appearance J:226655
normal endocrine/exocrine gland phenotype J:226655
neonatal lethality, incomplete penetrance J:226655
normal nervous system phenotype J:226655
postnatal lethality, incomplete penetrance J:226655
Alktm2.1Ics/Alktm2.1Ics
involves: 129S2/SvPas * C57BL/6
abnormal stellate ganglion morphology J:228124
abnormal superior cervical ganglion morphology J:228124
abnormal sympathetic ganglion morphology J:228124
enlarged superior cervical ganglion J:228124

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory