Uchl1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Uchl1
ubiquitin carboxy-terminal hydrolase L1
MGI:103149

43 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Uchl1^gad-2J/Uchl1^gad-2J B6.Cg-Uchl1^gad-2J/GrsrJ	abnormal locomotor coordination	J:161692
	ataxia	J:161692
	neurodegeneration	J:161692
	paralysis	J:161692
	premature death	J:161692
	weight loss	J:161692
Uchl1^gad-J/Uchl1^gad-J involves: BALB/c * C57BL/6	impaired coordination	J:142436
	premature death	J:142436
	weight loss	J:142436
Uchl1^gad/Uchl1^gad involves: CBA/Nga * RFM/Nga	abnormal dorsal root ganglion morphology	J:71819
	abnormal gait	J:71819
	abnormal hindlimb morphology	J:30954
	abnormal medulla oblongata morphology	J:30954
	abnormal spinal cord dorsal column morphology	J:30954
	abnormal stationary movement	J:30954
	ataxia	J:30954, J:71819
	axon degeneration	J:30954
	axonal dystrophy	J:71819
	normal cardiovascular system phenotype	J:30954
	decreased body weight	J:71819
	normal digestive/alimentary phenotype	J:30954
	normal hematopoietic system phenotype	J:30954
	normal liver/biliary system phenotype	J:30954
	paralysis	J:71819
	premature death	J:30954, J:71819
	normal renal/urinary system phenotype	J:30954
	normal respiratory system phenotype	J:30954
	tremors	J:30954
	weight loss	J:30954
Uchl1^gad/Uchl1^gad Not Specified	axon degeneration	J:28526
Uchl1^gad/Uchl1^gad Not Specified	motor neuron degeneration	J:28526
Uchl1^{tm1b(EUCOMM)Hmgu}/Uchl1⁺ C57BL/6N-Uchl1^{tm1b(EUCOMM)Hmgu}/H	abnormal spine curvature	J:211773
	hyperactivity	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased startle reflex	J:211773
Uchl1^tm1Dgen/Uchl1^tm1Dgen B6.129P2-Uchl1^tm1Dgen/Mmnc	abnormal endplate potential	J:156538
	abnormal gait	J:156538
	abnormal miniature endplate potential	J:156538
	abnormal neuromuscular synapse morphology	J:156538
	abnormal PNS synaptic transmission	J:156538
	abnormal synaptic plasticity	J:156538
	axon degeneration	J:156538
	decreased neurotransmitter release	J:156538
	decreased paired-pulse facilitation	J:156538
	forelimb paralysis	J:156538
	hindlimb paralysis	J:156538
	increased synaptic depression	J:156538
	kyphosis	J:156538
	limb grasping	J:156538
	motor neuron degeneration	J:156538
	premature death	J:156538
Uchl1^tm1Dgen/Uchl1^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	decreased grip strength	J:207278
	impaired coordination	J:101679, J:207278
	increased coping response	J:101679
	increased thermal nociceptive threshold	J:101679
	weight loss	J:207278

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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