75 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Eya1tm1Rilm/Eya1+ Pax2tm1Pgr/Pax2+ Six1tm1Mair/Six1+ involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cochlea morphology	J:119574
	abnormal semicircular canal ampulla morphology	J:119574
	abnormal semicircular canal morphology	J:119574
	abnormal vestibular saccule morphology	J:119574
	decreased cochlea coiling	J:119574
	decreased lateral semicircular canal size	J:119574
	decreased posterior semicircular canal size	J:119574
	decreased superior semicircular canal size	J:119574
	short endolymphatic duct	J:119574
	small vestibular saccule	J:119574
Eya1tm1Rilm/Eya1+ Six1tm1Mair/Six1+ involves: 129/Sv * 129S1/Sv * 129X1/SvJ	abnormal ureteric bud morphology	J:83432
	absent kidney	J:83432
	impaired branching involved in ureteric bud morphogenesis	J:83432
	renal hypoplasia	J:83432
	single kidney	J:83432
Eya1tm1Rilm/Eya1+ Six1tm1Mair/Six1+ involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal ureteric bud morphology	J:83432
	impaired branching involved in ureteric bud morphogenesis	J:83432
	renal hypoplasia	J:83432
	single kidney	J:83432
Eya1tm1Rilm/Eya1+ Six1tm1Mair/Six1+ involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cochlea morphology	J:119574
	abnormal inner ear morphology	J:119574
	abnormal semicircular canal ampulla morphology	J:119574
	abnormal semicircular canal morphology	J:119574
	abnormal vestibular saccule morphology	J:119574
	decreased cochlea coiling	J:119574
	decreased lateral semicircular canal size	J:119574
	decreased posterior semicircular canal size	J:119574
	decreased superior semicircular canal size	J:119574
	short endolymphatic duct	J:119574
Eya1tm1Rilm/Eya1+ Six1tm1Mair/Six1tm1Mair involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cardiac outflow tract development	J:172023
	abnormal common carotid artery morphology	J:172023
	double outlet right ventricle	J:172023
	retroesophageal right subclavian artery	J:172023
	right aortic arch	J:172023
Eya1tm1Rilm/Eya1+ Six1tm1Rsd/Six1+ involves: 129S1/Sv * 129X1/SvJ	renal hypoplasia	J:86619
	single kidney	J:86619
Eya1tm1Rilm/Eya1tm1Rilm Six1tm1Mair/Six1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cardiac outflow tract development	J:172023
	double outlet right ventricle	J:172023
	interrupted aortic arch	J:172023
	retroesophageal right subclavian artery	J:172023
	vascular ring	J:172023
Eya1tm1Rilm/Eya1tm1Rilm Six1tm1Mair/Six1tm1Mair involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cardiac outflow tract development	J:172023
	abnormal craniofacial development	J:172023
	abnormal extraocular muscle morphology	J:172023
	abnormal pulmonary artery morphology	J:172023
	abnormal skeletal muscle morphology	J:172023
	decreased cell proliferation	J:172023
	double outlet right ventricle	J:172023
	facial muscle hypoplasia	J:172023
	increased apoptosis	J:172023
	interrupted aortic arch, type b	J:172023
	persistent truncus arteriosus	J:172023
	retroesophageal right subclavian artery	J:172023
	right aortic arch	J:172023
	tongue muscle hypoplasia	J:172023
	vascular ring	J:172023
Eya1tm1Rilm/Eya1tm1Rilm Six1tm1Rsd/Six1tm1Rsd involves: 129S1/Sv * 129X1/SvJ	abnormal epaxial muscle morphology	J:86619
	absent hypaxial muscle	J:86619
	absent kidney	J:86619
	pituitary gland hypoplasia	J:86619
	small pituitary gland	J:86619
Fgf8tm1.3Mrt/Fgf8+ Six1tm1(cre)Xli/Six1+ involves: 129 * 129P2/OlaHsd * C57BL/6	abnormal cardiac outflow tract development	J:172023
	cervical aortic arch	J:172023
	interrupted aortic arch	J:172023
Jag1Mhdahtu/Jag1+ Six1Cwe/Six1+ C3HeB/FeJ-C3HeB/FeJ-Jag1Htu Six1Cwe	abnormal crista ampullaris morphology	J:149467
	abnormal inner ear canal morphology	J:149467
	abnormal posterior semicircular canal morphology	J:149467
	abnormal superior semicircular canal morphology	J:149467
	circling	J:149467
	head bobbing	J:149467
Six1tm1Kwk/Six1tm1Kwk Six4tm1Kwk/Six4tm1Kwk involves: 129P2/OlaHsd	abnormal dorsal root ganglion morphology	J:103002
	neonatal lethality, complete penetrance	J:103002
Six1tm1Mair/Six1tm1Mair Six4tm1Mair/Six4tm1Mair either: 129/Sv-Six1tm1Mair Six4tm1Mair or B6N.129-Six1tm1Mair Six4tm1Mair	abnormal forelimb morphology	J:98519
	abnormal genioglossus muscle morphology	J:98519
	abnormal hindlimb morphology	J:98519
	abnormal inner ear morphology	J:98519
	abnormal intrinsic tongue muscle morphology	J:98519
	abnormal muscle development	J:98519
	abnormal muscle precursor cell migration	J:98519
	abnormal skeletal muscle morphology	J:98519
	abnormal sternocostal joint morphology	J:98519
	absent eye muscles	J:98519
	absent hypaxial muscle	J:98519
	absent maxillary shelf	J:98519
	absent Meckel's cartilage	J:98519
	absent nasal bone	J:98519
	absent premaxilla	J:98519
	absent tongue muscles	J:98519
	absent tympanic ring	J:98519
	absent zygomatic bone	J:98519
	anotia	J:98519
	decreased embryo size	J:98519
	distended abdomen	J:98519
	exophthalmos	J:98519
	eyelids open at birth	J:98519
	muscle hypoplasia	J:98519
	perinatal lethality, complete penetrance	J:98519
	short mandible	J:98519
	short maxilla	J:98519
	short ribs	J:98519
	small orbits	J:98519
	small temporal bone	J:98519
	trunk curl	J:98519
Six1tm1Mair/Six1tm1Mair Tbx1tm1Bem/Tbx1tm1Bem involves: 129 * C57BL/6 * CD-1 * SJL	abnormal cardiovascular development	J:172023