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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pou4f2
POU domain, class 4, transcription factor 2
MGI:102524
23 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atoh7tm1Gan/Atoh7tm1Gan
Pou4f2tm1Nat/Pou4f2tm1Nat
B6.Cg-Pou4f2tm1Nat Atoh7tm1Gan 		abnormal eye electrophysiology J:135827
abnormal Muller cell morphology J:135827
abnormal retina ganglion cell morphology J:135827
abnormal retina morphology J:135827
abnormal retina rod bipolar cell morphology J:135827
decreased amacrine cell number J:135827
decreased retina ganglion cell number J:135827
increased retina apoptosis J:135827
retina hypoplasia J:135827
thin retina ganglion layer J:135827
thin retina inner nuclear layer J:135827
thin retina outer nuclear layer J:135827
Isl1tm1Gan/Isl1tm2Gan
Pou4f2tm1(ALPP)Whk/Pou4f2tm2Whk
Tg(Six3-cre)69Frty/?
involves: 129S6/SvEvTac * C57BL/6 * DBA/2 		optic nerve hypoplasia J:134978
retina ganglion cell degeneration J:134978
Isl1tm2Gan/Isl1tm2Gan
Pou4f2tm1(ALPP)Whk/Pou4f2tm2Whk
Tg(Six3-cre)69Frty/?
involves: 129S6/SvEvTac * C57BL/6 * DBA/2 		optic nerve hypoplasia J:134978
retina ganglion cell degeneration J:134978
Opn4tm1.1(cre)Saha/Opn4tm1Yau
Pou4f2tm4(DTA)Whk/Pou4f2+
involves: 129S/SvEv * C57BL/6 		abnormal innervation J:174940
abnormal olivary pretectal nucleus morphology J:174940
decreased retina ganglion cell number J:174940
Pou4f1tm1.1Gan/Pou4f1tm1.1Gan
Pou4f2tm2.1Gan/Pou4f2tm2.1Gan
Tg(CAG-cre/Esr1*)5Amc/0
Not Specified 		abnormal eye physiology J:215207
normal vision/eye phenotype J:215207
Pou4f2tm3Whk/Pou4f2tm3Whk
Pou4f3tm1Whk/Pou4f3tm1Whk
Not Specified 		abnormal retina ganglion cell morphology J:73779
abnormal retina morphology J:73779
abnormal retina nerve fiber layer morphology J:73779
abnormal sensory neuron innervation pattern J:73779
abnormal vestibular system physiology J:73779
deafness J:73779
decreased retina ganglion cell number J:73779
increased amacrine cell number J:73779
thin retina ganglion layer J:73779
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory