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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pou4f3
POU domain, class 4, transcription factor 3
MGI:102523
60 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Pou4f3ddl/Pou4f3ddl
C57BL/6J-Pou4f3ddl/J
abnormal cochlear outer hair cell morphology J:92833
abnormal outer hair cell stereociliary bundle morphology J:92833
absent pinna reflex J:55448
circling J:55448, J:92833
cochlear hair cell degeneration J:92833
cochlear inner hair cell degeneration J:92833
cochlear outer hair cell degeneration J:92833
deafness J:55448, J:92833
decreased body size J:55448
head tossing J:55448, J:92833
hyperactivity J:55448, J:92833
increased or absent threshold for auditory brainstem response J:55448, J:92833
pillar cell degeneration J:92833
Pou4f3tm1.1Nat/Pou4f3tm1.1Nat
B6.129-Pou4f3tm1.1Nat
no abnormal phenotype detected J:177259
Pou4f3tm1Rsd/Pou4f3+
involves: 129S4/SvJae * C57BL/6
normal hearing/vestibular/ear phenotype J:57149
Pou4f3tm1Rsd/Pou4f3tm1Rsd
involves: 129S4/SvJae
abnormal cochlea morphology J:207266
abnormal cochlear hair cell development J:33502
abnormal cochlear inner hair cell morphology J:33502
abnormal cochlear outer hair cell morphology J:33502
abnormal cochlear sensory epithelium morphology J:207266
abnormal cuticular plate morphology J:207266
abnormal motor coordination/balance J:33502
abnormal organ of Corti morphology J:33502
abnormal vestibulocochlear ganglion morphology J:207266
absent cochlear hair cell stereocilia J:33502, J:207266
absent cochlear hair cells J:33502, J:207266
absent inner hair cell stereocilia J:33502
absent organ of Corti supporting cells J:33502
absent outer hair cell stereocilia J:33502
absent tunnel of Corti J:207266
absent vestibular hair cell stereocilia J:33502
absent vestibular hair cells J:33502
cochlear ganglion degeneration J:33502
deafness J:33502
hyperactivity J:33502
increased or absent threshold for auditory brainstem response J:33502
vestibular ganglion degeneration J:33502
Pou4f3tm1Rsd/Pou4f3tm1Rsd
involves: 129S4/SvJae * C57BL/6
abnormal autonomic nervous system physiology J:81013
abnormal basilar membrane morphology J:57149
abnormal body temperature homeostasis J:81013
abnormal circadian temperature homeostasis J:81013
abnormal cochlea morphology J:57149
abnormal cochlear ganglion morphology J:57149
abnormal organ of Corti supporting cell differentiation J:57149
absent cochlear hair cells J:57149
circling J:57149
cochlear ganglion degeneration J:57149
deafness J:57149
degeneration of organ of Corti supporting cells J:57149
hyperactivity J:57149
organ of Corti degeneration J:57149
small Rosenthal canal J:57149
stria vascularis degeneration J:57149
Pou4f3tm1Whk/Pou4f3tm1Whk
Not Specified
abnormal inner ear vestibule morphology J:73779
abnormal vestibular system physiology J:73779
Pou4f3tm1Xia/Pou4f3tm1Xia
involves: 129S7/SvEvBrd * C57BL/6J
abnormal cochlear hair cell development J:82156
abnormal cochlear inner hair cell morphology J:92833
abnormal cochlear outer hair cell morphology J:82156, J:92833
abnormal crista ampullaris neuroepithelium morphology J:42478
abnormal Deiters cell morphology J:42478
abnormal energy expenditure J:42478
abnormal organ of Corti morphology J:42478, J:82156
abnormal outer hair cell stereociliary bundle morphology J:92833
abnormal pillar cell differentiation J:82156
abnormal sensory neuron innervation pattern J:82156
abnormal vestibular hair cell development J:43752, J:82156
absent cochlear hair cell stereocilia J:42478, J:43752
absent Deiters cells J:82156
absent inner hair cell stereocilia J:92833
absent organ of Corti supporting cells J:42478
absent pillar cells J:42478
absent vestibular hair cell stereocilia J:43752
circling J:42478
cochlear ganglion degeneration J:42478, J:43752, J:82156
cochlear hair cell degeneration J:42478, J:43752, J:92833
cochlear inner hair cell degeneration J:42478, J:92833
cochlear outer hair cell degeneration J:42478, J:92833
deafness J:42478
decreased body size J:42478
decreased body weight J:42478
decreased startle reflex J:42478
impaired balance J:42478
impaired swimming J:42478
increased or absent threshold for auditory brainstem response J:42478
pillar cell degeneration J:92833
reduced fertility J:42478
small vestibular ganglion J:82156
vestibular ganglion degeneration J:42478, J:43752, J:82156
vestibular hair cell degeneration J:42478, J:43752

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory