GO Annotations Graph

• Symbol: Epha3
• Name: Eph receptor A3
• ID: MGI:99612

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005003	ephrin receptor activity	ISO	J:164563
Molecular Function	GO:0005003	ephrin receptor activity	IDA	J:91751
Molecular Function	GO:0005004	GPI-linked ephrin receptor activity	ISO	J:164563
Molecular Function	GO:0019838	growth factor binding	IPI	J:297316
Molecular Function	GO:0019838	growth factor binding	IPI	J:297316
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:152203
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:60000
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:72247
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IEA	J:72245
Molecular Function	GO:0005005	transmembrane-ephrin receptor activity	IBA	J:265628
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030425	dendrite	IBA	J:265628
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0098982	GABA-ergic synapse	IC	J:204427
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:204427
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:204427
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:204427
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:204427
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:204427
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:204427
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:204427
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:204427
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-3928661
Cellular Component	GO:0098793	presynapse	IDA	J:204427
Cellular Component	GO:0098793	presynapse	IDA	J:204427
Biological Process	GO:0007411	axon guidance	IBA	J:265628
Biological Process	GO:0016477	cell migration	IMP	J:119874
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	IDA	J:194293
Biological Process	GO:0071300	cellular response to retinoic acid	ISO	J:164563
Biological Process	GO:0003197	endocardial cushion development	IMP	J:119874
Biological Process	GO:0048013	ephrin receptor signaling pathway	IDA	J:168688
Biological Process	GO:0048013	ephrin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0048013	ephrin receptor signaling pathway	IBA	J:265628
Biological Process	GO:0097156	fasciculation of motor neuron axon	IMP	J:133671
Biological Process	GO:0097155	fasciculation of sensory neuron axon	IMP	J:174684
Biological Process	GO:0045806	negative regulation of endocytosis	ISO	J:164563
Biological Process	GO:0010977	negative regulation of neuron projection development	IDA	J:152203
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:164563
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IBA	J:265628
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0030334	regulation of cell migration	IGI	J:152203
Biological Process	GO:0010717	regulation of epithelial to mesenchymal transition	IMP	J:119874
Biological Process	GO:0051893	regulation of focal adhesion assembly	ISO	J:164563
Biological Process	GO:0043087	regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	ISO	J:164563
Biological Process	GO:0099560	synaptic membrane adhesion	IDA	J:204427
Biological Process	GO:0099560	synaptic membrane adhesion	IMP	J:204427
Biological Process	GO:0099560	synaptic membrane adhesion	IDA	J:204427
Biological Process	GO:0099560	synaptic membrane adhesion	IPI	J:204427
Biological Process	GO:0099560	synaptic membrane adhesion	IMP	J:204427
Biological Process	GO:0099560	synaptic membrane adhesion	IPI	J:204427
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IEA	J:72247