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GO Annotations Graph
Symbol
Name
ID
Hsf1
heat shock factor 1
MGI:96238

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003682chromatin bindingIDAJ:175085
Molecular FunctionGO:0003677DNA bindingIDAJ:74044
Molecular FunctionGO:0031072heat shock protein bindingISOJ:155856
Molecular FunctionGO:1990841promoter-specific chromatin bindingISOJ:155856
Molecular FunctionGO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingISOJ:164563
Molecular FunctionGO:0000979RNA polymerase II core promoter sequence-specific DNA bindingIDAJ:140801
Molecular FunctionGO:0001162RNA polymerase II intronic transcription regulatory region sequence-specific DNA bindingISOJ:73065
Molecular FunctionGO:0043565sequence-specific DNA bindingIDAJ:142548
Molecular FunctionGO:0098847sequence-specific single stranded DNA bindingISOJ:155856
Molecular FunctionGO:0097677STAT family protein bindingISOJ:155856
Molecular FunctionGO:0003700transcription factor activity, sequence-specific DNA bindingIEAJ:72247
Molecular FunctionGO:0001078transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific bindingISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:91051
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737cytoplasmIDAJ:74044
Cellular ComponentGO:0000791euchromatinISOJ:155856
Cellular ComponentGO:0000792heterochromatinISOJ:155856
Cellular ComponentGO:0005654nucleoplasmISOJ:164563
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0005634nucleusIDAJ:74044
Cellular ComponentGO:0005634nucleusIDAJ:140801
Cellular ComponentGO:0045120pronucleusIDAJ:91051
Cellular ComponentGO:0043234protein complexIPIJ:125219
Biological ProcessGO:0071230cellular response to amino acid stimulusISOJ:155856
Biological ProcessGO:1904385cellular response to angiotensinISOJ:155856
Biological ProcessGO:0071392cellular response to estradiol stimulusISOJ:155856
Biological ProcessGO:0034605cellular response to heatISOJ:155856
Biological ProcessGO:0034605cellular response to heatISOJ:164563
Biological ProcessGO:0070301cellular response to hydrogen peroxideISOJ:155856
Biological ProcessGO:0071407cellular response to organic cyclic compoundISOJ:155856
Biological ProcessGO:0071478cellular response to radiationISOJ:155856
Biological ProcessGO:0006952defense responseISOJ:155856
Biological ProcessGO:0001892embryonic placenta developmentIMPJ:58383
Biological ProcessGO:0060136embryonic process involved in female pregnancyIMPJ:58383
Biological ProcessGO:0007143female meiotic divisionIMPJ:175085
Biological ProcessGO:0001701in utero embryonic developmentIMPJ:58383
Biological ProcessGO:0009299mRNA transcriptionISOJ:164563
Biological ProcessGO:0010667negative regulation of cardiac muscle cell apoptotic processISOJ:155856
Biological ProcessGO:0008285negative regulation of cell proliferationIGIJ:93301
Biological ProcessGO:0010629negative regulation of gene expressionISOJ:155856
Biological ProcessGO:0090084negative regulation of inclusion body assemblyISOJ:155856
Biological ProcessGO:1901215negative regulation of neuron deathISOJ:155856
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0032720negative regulation of tumor necrosis factor productionIMPJ:58383
Biological ProcessGO:1902512positive regulation of apoptotic DNA fragmentationISOJ:155856
Biological ProcessGO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic processISOJ:155856
Biological ProcessGO:0010628positive regulation of gene expressionISOJ:155856
Biological ProcessGO:0090261positive regulation of inclusion body assemblyISOJ:155856
Biological ProcessGO:1904528positive regulation of microtubule bindingISOJ:155856
Biological ProcessGO:0040018positive regulation of multicellular organism growthIMPJ:58383
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:73065
Biological ProcessGO:0042517positive regulation of tyrosine phosphorylation of Stat3 proteinISOJ:155856
Biological ProcessGO:0006468protein phosphorylationIDAJ:142548
Biological ProcessGO:0090231regulation of spindle checkpointIMPJ:175085
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:72247
Biological ProcessGO:0032355response to estradiolISOJ:155856
Biological ProcessGO:0009408response to heatIMPJ:58383
Biological ProcessGO:0009408response to heatISOJ:155856
Biological ProcessGO:0032496response to lipopolysaccharideIMPJ:58383
Biological ProcessGO:0033574response to testosteroneISOJ:155856
Biological ProcessGO:0007283spermatogenesisIGIJ:88035
Biological ProcessGO:0006351transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0006351transcription, DNA-templatedIEAJ:72247


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory