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GO Annotations Graph
Symbol
Name
ID
Gli3
GLI-Kruppel family member GLI3
MGI:95729

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0008013beta-catenin bindingISOJ:164563
Molecular FunctionGO:0003682chromatin bindingIGIJ:104380
Molecular FunctionGO:0003677DNA bindingIEAJ:60000
Molecular FunctionGO:0035035histone acetyltransferase bindingISOJ:164563
Molecular FunctionGO:0042826histone deacetylase bindingISOJ:164563
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:72247
Molecular FunctionGO:0003676nucleic acid bindingIEAJ:72247
Molecular FunctionGO:0005515protein bindingIPIJ:63778
Molecular FunctionGO:0005515protein bindingIPIJ:207249
Molecular FunctionGO:0005515protein bindingIPIJ:149459
Molecular FunctionGO:0005515protein bindingIPIJ:152259
Molecular FunctionGO:0005515protein bindingIPIJ:158961
Molecular FunctionGO:0005515protein bindingIPIJ:151923
Molecular FunctionGO:0005515protein bindingIPIJ:80205
Molecular FunctionGO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingISOJ:73065
Molecular FunctionGO:0000977RNA polymerase II regulatory region sequence-specific DNA bindingISOJ:73065
Molecular FunctionGO:0043565sequence-specific DNA bindingIDAJ:108433
Molecular FunctionGO:0003700transcription factor activity, sequence-specific DNA bindingISOJ:155856
Molecular FunctionGO:0003700transcription factor activity, sequence-specific DNA bindingISOJ:164563
Molecular FunctionGO:0003700transcription factor activity, sequence-specific DNA bindingIDAJ:169807
Cellular ComponentGO:0005930axonemeISOJ:155856
Cellular ComponentGO:0005930axonemeIDAJ:168317
Cellular ComponentGO:0042995cell projectionIEAJ:60000
Cellular ComponentGO:0005929ciliumISOJ:164563
Cellular ComponentGO:0005929ciliumISOJ:115756
Cellular ComponentGO:0005929ciliumIDAJ:182871
Cellular ComponentGO:0005737cytoplasmIDAJ:151923
Cellular ComponentGO:0005737cytoplasmIDAJ:158961
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:80205
Cellular ComponentGO:0005737cytoplasmIDAJ:207249
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005829cytosolISOJ:164563
Cellular ComponentGO:0016592colocalizes_with
mediator complex
ISOJ:164563
Cellular ComponentGO:0016607nuclear speckIDAJ:151923
Cellular ComponentGO:0005634nucleusIDAJ:207249
Cellular ComponentGO:0005634nucleusIDAJ:151923
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0005634nucleusIDAJ:80205
Cellular ComponentGO:0005634nucleusIDAJ:158961
Cellular ComponentGO:0005634nucleusISOJ:73065
Cellular ComponentGO:0005634nucleusISOJ:115756
Cellular ComponentGO:0072372primary ciliumIDAJ:151923
Cellular ComponentGO:0072372primary ciliumISOJ:155856
Cellular ComponentGO:0072372primary ciliumIDAJ:212094
Cellular ComponentGO:0072372primary ciliumIDAJ:168317
Cellular ComponentGO:0017053transcriptional repressor complexIDAJ:80205
Biological ProcessGO:0048856anatomical structure developmentIGIJ:70870
Biological ProcessGO:0048646anatomical structure formation involved in morphogenesisIGIJ:49603
Biological ProcessGO:0060873anterior semicircular canal developmentIMPJ:121232
Biological ProcessGO:0009952anterior/posterior pattern specificationIMPJ:188038
Biological ProcessGO:0009952anterior/posterior pattern specificationIGIJ:188038
Biological ProcessGO:0009952anterior/posterior pattern specificationIMPJ:92507
Biological ProcessGO:0060840artery developmentIGIJ:119563
Biological ProcessGO:0007411axon guidanceIMPJ:109287
Biological ProcessGO:0007411axon guidanceIMPJ:165487
Biological ProcessGO:0007420brain developmentIMPJ:17581
Biological ProcessGO:0007420brain developmentIMPJ:121232
Biological ProcessGO:0007420brain developmentIMPJ:80177
Biological ProcessGO:0001658branching involved in ureteric bud morphogenesisIGIJ:104380
Biological ProcessGO:0048754branching morphogenesis of an epithelial tubeIMPJ:102853
Biological ProcessGO:0043010camera-type eye developmentIGIJ:139168
Biological ProcessGO:0048593camera-type eye morphogenesisIMPJ:4086
Biological ProcessGO:0061005cell differentiation involved in kidney developmentIGIJ:154102
Biological ProcessGO:0007417central nervous system developmentIMPJ:80207
Biological ProcessGO:0007417central nervous system developmentIGIJ:80206
Biological ProcessGO:0021801cerebral cortex radial glia guided migrationIMPJ:43330
Biological ProcessGO:0048589developmental growthIMPJ:42454
Biological ProcessGO:0009953dorsal/ventral pattern formationIMPJ:108509
Biological ProcessGO:0009953dorsal/ventral pattern formationIMPJ:80207
Biological ProcessGO:0009953dorsal/ventral pattern formationIMPJ:87948
Biological ProcessGO:0048566embryonic digestive tract developmentIMPJ:60446
Biological ProcessGO:0048557embryonic digestive tract morphogenesisIMPJ:102853
Biological ProcessGO:0042733embryonic digit morphogenesisIMPJ:115756
Biological ProcessGO:0042733embryonic digit morphogenesisIGIJ:128015
Biological ProcessGO:0042733embryonic digit morphogenesisIMPJ:188038
Biological ProcessGO:0042733embryonic digit morphogenesisIMPJ:42445
Biological ProcessGO:0042733embryonic digit morphogenesisIMPJ:142500
Biological ProcessGO:0042733embryonic digit morphogenesisIGIJ:42445
Biological ProcessGO:0030326embryonic limb morphogenesisIGIJ:102948
Biological ProcessGO:0030326embryonic limb morphogenesisIMPJ:80205
Biological ProcessGO:0030326embryonic limb morphogenesisIMPJ:4086
Biological ProcessGO:0030326embryonic limb morphogenesisIMPJ:78407
Biological ProcessGO:0030326embryonic limb morphogenesisIMPJ:80177
Biological ProcessGO:0030326embryonic limb morphogenesisIGIJ:150759
Biological ProcessGO:0030326embryonic limb morphogenesisIMPJ:154102
Biological ProcessGO:0048598embryonic morphogenesisIMPJ:4086
Biological ProcessGO:0048568embryonic organ developmentIEAJ:72247
Biological ProcessGO:0048704embryonic skeletal system morphogenesisIGIJ:101708
Biological ProcessGO:0030900forebrain developmentIMPJ:103594
Biological ProcessGO:0021798forebrain dorsal/ventral pattern formationIMPJ:59923
Biological ProcessGO:0021861forebrain radial glial cell differentiationIMPJ:43330
Biological ProcessGO:0060364frontal suture morphogenesisIMPJ:163175
Biological ProcessGO:0007507heart developmentIGIJ:113186
Biological ProcessGO:0007442hindgut morphogenesisIGIJ:70870
Biological ProcessGO:0021766hippocampus developmentIMPJ:203028
Biological ProcessGO:0001701in utero embryonic developmentIMPJ:115756
Biological ProcessGO:0048839inner ear developmentIGIJ:121232
Biological ProcessGO:0001822kidney developmentIGIJ:113186
Biological ProcessGO:0060366lambdoid suture morphogenesisIMPJ:163175
Biological ProcessGO:0022018lateral ganglionic eminence cell proliferationIMPJ:165487
Biological ProcessGO:0060875lateral semicircular canal developmentIMPJ:121232
Biological ProcessGO:0021819layer formation in cerebral cortexIMPJ:171423
Biological ProcessGO:0060173limb developmentIMPJ:121609
Biological ProcessGO:0060173limb developmentISOJ:155856
Biological ProcessGO:0035108limb morphogenesisIMPJ:42445
Biological ProcessGO:0035108limb morphogenesisISOJ:164563
Biological ProcessGO:0030324lung developmentIGIJ:92194
Biological ProcessGO:0030324lung developmentIMPJ:42454
Biological ProcessGO:0030879mammary gland developmentIMPJ:112460
Biological ProcessGO:0060594mammary gland specificationIGIJ:109476
Biological ProcessGO:0030318melanocyte differentiationIMPJ:136642
Biological ProcessGO:0001656metanephros developmentIGIJ:104380
Biological ProcessGO:0046639negative regulation of alpha-beta T cell differentiationIMPJ:151855
Biological ProcessGO:0046639negative regulation of alpha-beta T cell differentiationISOJ:155856
Biological ProcessGO:0043066negative regulation of apoptotic processIMPJ:145009
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayISOJ:164563
Biological ProcessGO:0045596negative regulation of cell differentiationIGIJ:102948
Biological ProcessGO:0008285negative regulation of cell proliferationIMPJ:163175
Biological ProcessGO:0008285negative regulation of cell proliferationIGIJ:163175
Biological ProcessGO:0008285negative regulation of cell proliferationIGIJ:104380
Biological ProcessGO:0008285negative regulation of cell proliferationIMPJ:121301
Biological ProcessGO:0008285negative regulation of cell proliferationIMPJ:104380
Biological ProcessGO:0045665negative regulation of neuron differentiationIMPJ:145009
Biological ProcessGO:0045879negative regulation of smoothened signaling pathwayIMPJ:151855
Biological ProcessGO:0045879negative regulation of smoothened signaling pathwayISOJ:155856
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterISOJ:73065
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedIMPJ:219044
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedIMPJ:121609
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedIDAJ:80205
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedISOJ:155856
Biological ProcessGO:0045060negative thymic T cell selectionIMPJ:151855
Biological ProcessGO:0045060negative thymic T cell selectionISOJ:155856
Biological ProcessGO:0021915neural tube developmentIMPJ:4086
Biological ProcessGO:0048663neuron fate commitmentIMPJ:103594
Biological ProcessGO:0042475odontogenesis of dentin-containing toothIGIJ:49252
Biological ProcessGO:0048709oligodendrocyte differentiationIGIJ:119850
Biological ProcessGO:0021631optic nerve morphogenesisIMPJ:106158
Biological ProcessGO:0060021palate developmentIMPJ:139635
Biological ProcessGO:0021543pallium developmentIMPJ:53903
Biological ProcessGO:0007389pattern specification processIGIJ:87223
Biological ProcessGO:0046638positive regulation of alpha-beta T cell differentiationIMPJ:117284
Biological ProcessGO:0046638positive regulation of alpha-beta T cell differentiationISOJ:155856
Biological ProcessGO:0032332positive regulation of chondrocyte differentiationIMPJ:121301
Biological ProcessGO:0002052positive regulation of neuroblast proliferationIMPJ:165487
Biological ProcessGO:0045669positive regulation of osteoblast differentiationIGIJ:163175
Biological ProcessGO:0045669positive regulation of osteoblast differentiationIMPJ:163175
Biological ProcessGO:0042307positive regulation of protein import into nucleusIGIJ:113403
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIMPJ:151855
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:155856
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedISOJ:155856
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIDAJ:121301
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIMPJ:121609
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIMPJ:219044
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIDAJ:169807
Biological ProcessGO:0016485protein processingIDAJ:142500
Biological ProcessGO:0009954proximal/distal pattern formationIGIJ:106158
Biological ProcessGO:0009954proximal/distal pattern formationIMPJ:106158
Biological ProcessGO:0042981regulation of apoptotic processIMPJ:17581
Biological ProcessGO:1903010regulation of bone developmentIMPJ:188038
Biological ProcessGO:0045595regulation of cell differentiationIGIJ:102948
Biological ProcessGO:0042127regulation of cell proliferationIGIJ:117221
Biological ProcessGO:0010468regulation of gene expressionIGIJ:142755
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIMPJ:39658
Biological ProcessGO:0060367sagittal suture morphogenesisIMPJ:163175
Biological ProcessGO:0007224smoothened signaling pathwayIGIJ:104380
Biological ProcessGO:0007224smoothened signaling pathwayIGIJ:108509
Biological ProcessGO:0007224smoothened signaling pathwayIGIJ:113403
Biological ProcessGO:0007224smoothened signaling pathwayIGIJ:102948
Biological ProcessGO:0007224smoothened signaling pathwayIGIJ:80206
Biological ProcessGO:0060831smoothened signaling pathway involved in dorsal/ventral neural tube patterningIGIJ:121232
Biological ProcessGO:0060831smoothened signaling pathway involved in dorsal/ventral neural tube patterningIGIJ:158583
Biological ProcessGO:0021776smoothened signaling pathway involved in spinal cord motor neuron cell fate specificationIGIJ:92067
Biological ProcessGO:0021775smoothened signaling pathway involved in ventral spinal cord interneuron specificationIGIJ:92067
Biological ProcessGO:0021513spinal cord dorsal/ventral patterningIGIJ:92067
Biological ProcessGO:0021513spinal cord dorsal/ventral patterningIGIJ:104803
Biological ProcessGO:0021522spinal cord motor neuron differentiationIGIJ:188764
Biological ProcessGO:0021544subpallium developmentIMPJ:165487
Biological ProcessGO:0033077T cell differentiation in thymusIMPJ:117284
Biological ProcessGO:0033077T cell differentiation in thymusISOJ:155856
Biological ProcessGO:0033077T cell differentiation in thymusIMPJ:117284
Biological ProcessGO:0021537telencephalon developmentIMPJ:59923
Biological ProcessGO:0021537telencephalon developmentIMPJ:145009
Biological ProcessGO:0021537telencephalon developmentIMPJ:142500
Biological ProcessGO:0070242thymocyte apoptotic processIMPJ:151855
Biological ProcessGO:0070242thymocyte apoptotic processISOJ:155856
Biological ProcessGO:0043586tongue developmentIMPJ:139635
Biological ProcessGO:0006351transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0035295tube developmentIGIJ:49603


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/22/2022
MGI 6.21
The Jackson Laboratory