Dmrt1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Dmrt1
doublesex and mab-3 related transcription factor 1
MGI:1354733

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:196366
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:162401
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:166057
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:194811
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:194811
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:194811
Molecular Function	GO:0005515	protein binding	IPI	J:194811
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:194811
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:194811
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:175257
Cellular Component	GO:0001674	female germ cell nucleus	IDA	J:175257
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9690898
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9692206
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9692268
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9692296
Cellular Component	GO:0005634	nucleus	IDA	J:65541
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0000902	cell morphogenesis	IMP	J:122954
Biological Process	GO:0000902	cell morphogenesis	IMP	J:122954
Biological Process	GO:0003006	developmental process involved in reproduction	IGI	J:122954
Biological Process	GO:0008354	germ cell migration	IMP	J:122954
Biological Process	GO:0008354	germ cell migration	IMP	J:122954
Biological Process	GO:0035556	intracellular signal transduction	ISO	J:155856
Biological Process	GO:0002176	male germ cell proliferation	IMP	J:166057
Biological Process	GO:0002176	male germ cell proliferation	IMP	J:156489
Biological Process	GO:0008584	male gonad development	IMP	J:122954
Biological Process	GO:0008584	male gonad development	IMP	J:174935
Biological Process	GO:0008584	male gonad development	IMP	J:122954
Biological Process	GO:0030238	male sex determination	IMP	J:65541
Biological Process	GO:0030238	male sex determination	IMP	J:156489
Biological Process	GO:0030238	male sex determination	IMP	J:166057
Biological Process	GO:0046661	male sex differentiation	IMP	J:156489
Biological Process	GO:0046661	male sex differentiation	IMP	J:65541
Biological Process	GO:0046661	male sex differentiation	IMP	J:166057
Biological Process	GO:0007127	meiosis I	IMP	J:175257
Biological Process	GO:0007127	meiosis I	IMP	J:175257
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045835	negative regulation of meiotic nuclear division	IMP	J:166057
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:166057
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:162401
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:156489
Biological Process	GO:0048599	oocyte development	IMP	J:175257
Biological Process	GO:2000020	positive regulation of male gonad development	IMP	J:174935
Biological Process	GO:0060903	positive regulation of meiosis I	IMP	J:175257
Biological Process	GO:0045840	positive regulation of mitotic nuclear division	IMP	J:166057
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:162401
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:194811
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:166057
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:1900107	regulation of nodal signaling pathway	IMP	J:196366
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0060009	Sertoli cell development	IMP	J:174935
Biological Process	GO:0060008	Sertoli cell differentiation	IMP	J:65541
Biological Process	GO:0060008	Sertoli cell differentiation	IMP	J:122954
Biological Process	GO:0060008	Sertoli cell differentiation	IMP	J:122954
Biological Process	GO:0007548	sex differentiation	IBA	J:265628
Biological Process	GO:0007283	spermatogenesis	IMP	J:122954
Biological Process	GO:0007283	spermatogenesis	IMP	J:122954

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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