GO Annotations Graph

• Symbol: Ncoa1
• Name: nuclear receptor coactivator 1
• ID: MGI:1276523

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016746	acyltransferase activity	IEA	J:60000
Molecular Function	GO:0003682	chromatin binding	IDA	J:80609
Molecular Function	GO:0003682	chromatin binding	IDA	J:104056
Molecular Function	GO:0003677	DNA binding	IDA	J:96189
Molecular Function	GO:0004402	histone acetyltransferase activity	IEA	J:72245
Molecular Function	GO:0030331	nuclear estrogen receptor binding	ISO	J:155856
Molecular Function	GO:0030331	nuclear estrogen receptor binding	ISO	J:164563
Molecular Function	GO:0033142	nuclear progesterone receptor binding	ISO	J:155856
Molecular Function	GO:0016922	nuclear receptor binding	ISO	J:164563
Molecular Function	GO:0016922	nuclear receptor binding	ISO	J:155856
Molecular Function	GO:0016922	nuclear receptor binding	IBA	J:265628
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ISO	J:164563
Molecular Function	GO:0030374	nuclear receptor coactivator activity	IBA	J:265628
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	ISO	J:155856
Molecular Function	GO:0046965	nuclear retinoid X receptor binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:116733
Molecular Function	GO:0005515	protein binding	IPI	J:222684
Molecular Function	GO:0005515	protein binding	IPI	J:65012
Molecular Function	GO:0005515	protein binding	IPI	J:91558
Molecular Function	GO:0005515	protein binding	IPI	J:76833
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0003713	transcription coactivator activity	IMP	J:178277
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:116733
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-556760
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	EXP	J:320076
Biological Process	GO:0032870	cellular response to hormone stimulus	ISO	J:155856
Biological Process	GO:0032870	cellular response to hormone stimulus	IBA	J:265628
Biological Process	GO:1904017	cellular response to Thyroglobulin triiodothyronine	IGI	J:213682
Biological Process	GO:0060713	labyrinthine layer morphogenesis	IGI	J:182838
Biological Process	GO:0060179	male mating behavior	ISO	J:155856
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0035357	peroxisome proliferator activated receptor signaling pathway	NAS	J:319988
Biological Process	GO:1904179	positive regulation of adipose tissue development	NAS	J:319988
Biological Process	GO:0043065	positive regulation of apoptotic process	IMP	J:178277
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:76833
Biological Process	GO:0045925	positive regulation of female receptivity	ISO	J:155856
Biological Process	GO:0045666	positive regulation of neuron differentiation	IMP	J:178277
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NAS	J:320074
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:65012
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:91558
Biological Process	GO:0000435	positive regulation of transcription from RNA polymerase II promoter by galactose	ISO	J:164563
Biological Process	GO:1900076	regulation of cellular response to insulin stimulus	NAS	J:319988
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0002155	regulation of thyroid hormone mediated signaling pathway	IGI	J:213682
Biological Process	GO:0032355	response to estradiol	ISO	J:155856
Biological Process	GO:0032570	response to progesterone	ISO	J:155856
Biological Process	GO:0032526	response to retinoic acid	ISO	J:155856