Automated description from the Alliance of Genome Resources (Release 5.4.0)
Enables DNA binding activity; chromatin binding activity; and transcription coactivator activity. Involved in positive regulation of apoptotic process and positive regulation of neuron differentiation. Acts upstream of or within several processes, including cellular response to Thyroglobulin triiodothyronine; labyrinthine layer morphogenesis; and regulation of thyroid hormone mediated signaling pathway. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; brain; early conceptus; eye; and genitourinary system. Used to study obesity and thyroid hormone resistance syndrome. Orthologous to human NCOA1 (nuclear receptor coactivator 1).