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Creb3
Gene Detail
Symbol

Name
ID
Creb3
cAMP responsive element binding protein 3
MGI:99946
Synonyms
Luman, LZIP, LZIP-1, LZIP-2
Feature Type
protein coding gene
Genetic Map
Chromosome 4
23.05 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr4:43562332-43567060 bp, + strand
From VEGA annotation of GRCm38

  4729 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31375  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CREB3
Gene Tree: Creb3

Human
homologs
CREB3, cAMP responsive element binding protein 3
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 10488
neXtProt AC: NX_O43889

Human Synonyms: LUMAN, LZIP, sLZIP

Human Chr (Location): 9p13.3; chr9:35732320-35737008 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Creb3 interacts with 41 markers (Mir26b, Mir129-1, Mir129-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (45 annotations)
Process chemotaxis, cytoplasmic sequestering of transcription factor, ...
Component cytoplasm, cytosol, ...
Function cAMP response element binding, cAMP response element binding protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (170)    Tissues (74)    Images (27)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 162
RT-PCR 8
cDNA source data(17)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA CREB3 ; Xenbase creb3    NEW 
Molecular
reagents
All nucleic(18) cDNA(17) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000006960 (Evidence)
Ensembl Gene Model ENSMUSG00000028466 (Evidence)
Entrez Gene 12913 (Evidence)
NIA Mouse Gene Index U004236
Consensus CDS Project CCDS18102.1
International Mouse Phenotyping Consortium Status Creb3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006960 VEGA Gene Model | MGI Sequence Detail 4729 C57BL/6J ±  kb
transcript OTTMUST00000016122 VEGA | MGI Sequence Detail 1884 Not Applicable 
polypeptide OTTMUSP00000007395 VEGA | MGI Sequence Detail 379 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(2) UniProt(4)
Polymorphisms
RFLP(2) : SNPs within 2kb(32 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004827 Basic-leucine zipper domain
InterPro IPR008917 Eukaryotic transcription factor, Skn-1-like, DNA-binding
Protein Ontology PR:000005855 cyclic AMP-responsive element-binding protein 3
References
(Earliest) J:17005 Burbelo PD, et al., LZIP-1 and LZIP-2: two novel members of the bZIP family. Gene. 1994 Feb 25;139(2):241-5
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(39)
Other
accession IDs
MGD-MRK-16749, MGI:2140496, MGI:2140584, MGI:2140683

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory