Creb3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Creb3
cAMP responsive element binding protein 3
MGI:99946

27 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Creb3^Gt1Mbac/Creb3⁺ B6NTac.Cg-Creb3^Gt1Mbac	abnormal body composition	J:345514
	abnormal lipid level	J:345514
	abnormal phospholipid level	J:345514
	decreased body fat mass	J:345514
	decreased circulating insulin level	J:345514
	decreased circulating leptin level	J:345514
	decreased fasting circulating glucose level	J:345514
	decreased lean body mass	J:345514
	decreased liver triglyceride level	J:345514
	decreased percent body fat/body weight	J:345514
	decreased skeletal muscle triglyceride level	J:345514
	decreased susceptibility to diet-induced hepatic steatosis	J:345514
	decreased susceptibility to diet-induced obesity	J:345514
	decreased white fat cell size	J:345514
	normal homeostasis/metabolism phenotype	J:345514
	improved glucose tolerance	J:345514
	increased basal metabolism	J:345514
	increased energy expenditure	J:345514
	increased respiratory quotient	J:345514
	increased white fat cell number	J:345514
Creb3^Gt1Mbac/Creb3^Gt1Mbac B6NTac.Cg-Creb3^Gt1Mbac	decreased survivor rate	J:345514
Creb3^{tm1.1(KOMP)Vlcg}/Creb3⁺ C57BL/6N-Creb3^{tm1.1(KOMP)Vlcg}/Ucd	abnormal epididymis morphology	J:211773
	decreased body length	J:211773
	decreased brain weight	J:211773
	enlarged epididymis	J:211773
	hyperactivity	J:211773
Creb3^{tm1.1(KOMP)Vlcg}/Creb3^{tm1.1(KOMP)Vlcg} C57BL/6N-Creb3^{tm1.1(KOMP)Vlcg}/Ucd	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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