mt-Atp6
Gene Detail

Symbol Name ID

mt-Atp6 mitochondrially encoded ATP synthase 6 MGI:99927

Synonyms

ATPASE6

Feature Type

protein coding gene

Genetic Map

Chromosome MT
Syntenic

Sequence Map

ChrMT:7927-8607 bp, + strand From NCBI annotation of GRCm38   681 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5012  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: F-type ATP synthase, subunit a
Gene Tree: mt-Atp6

Human homologs

Human Homolog		ATP6, ATP synthase F0 subunit 6
NCBI Gene ID		4508
neXtProt AC		NX_P00846
Human Synonyms		ATPase6, MTATP6
Human Chr (Location)		MT
Disease Associations		(3) Diseases Associated with Human ATP6

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	ATP biosynthetic process, ATP synthesis coupled proton transport, ...
Component	integral to membrane, membrane, ...
Function	hydrogen ion transmembrane transporter activity, hydrolase activity

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (138)    Tissues (130)    Images (10)
Theiler Stages: 17, 20, 21, 22, 23, 24, 25, 26, 28

Assay Type	Results
RNA in situ	136
RT-PCR	2

cDNA source data(36)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(40) cDNA(36) Primer pair(2) Other(2)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000064357 (Evidence)
Entrez Gene	17705
DFCI	TC1576231
DoTS	DT.94221974, DT.94221990
International Mouse Knockout Project Status	mt-Atp6

Sequences

Length	Strain/Species
genomic	17705	NCBI Gene Model | MGI Sequence Detail	681	C57BL/6J
transcript	BC012020	GenBank | EMBL | DDBJ | MGI Sequence Detail	1616	C57BL/6
polypeptide	P00848	UniProt | EBI | MGI Sequence Detail	226	Not Applicable

All sequences(91) RefSeq(1) UniProt(5)

Protein-related information

Resource	ID	Description
InterPro	IPR000568	ATPase, F0 complex, subunit A
InterPro	IPR023011	ATPase, F0 complex, subunit A, active site

Graphical View of Protein Domain Structure

References

(Earliest) J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
(Latest) J:170357 Honda JY, et al., In situ expression of the mitochondrial ATPase6 gene in the developing tooth germ of the mouse lower first molar. J Mol Histol. 2011 Feb;42(1):83-90
All references(31)

Other accession IDs

MGD-MRK-16729, MGI:2138390, MGI:2138397, MGI:2138428, MGI:2138431, MGI:2138433, MGI:2138437, MGI:2138438, MGI:2138440, MGI:2138444, MGI:2138445, MGI:2138449, MGI:2138458, MGI:2138460, MGI:2138461, MGI:2138463