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mt-Atp8
Gene Detail
 Symbol
Name
ID
mt-Atp8
mitochondrially encoded ATP synthase 8
MGI:99926
Synonyms URFA6L
Feature Type protein coding gene
Genetic Map
Chromosome MT
Syntenic
Sequence Map
ChrMT:7766-7969 bp, + strand
From Ensembl annotation of GRCm38

  204 bp   ±  kb flank

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Mouse Genome Browser
Vertebrate
homology
HomoloGene:5020  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: F-type ATP synthase, subunit 8, animal type
Gene Tree: mt-Atp8

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Spontaneous(1)
 
Mice carrying homoplastic mtDNAs with a single point mutation in this gene exhibit increased anxiety-like behavior.
 
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process ATP biosynthetic process, ATP synthesis coupled proton transport, ...
Component integral component of membrane, membrane, ...
Function hydrogen ion transmembrane transporter activity, hydrolase activity, ...
Expression
Literature Summary: (1 records)
External Resources: Expression Atlas
Molecular
reagents
All nucleic(52) Other(52)
Other database
links
Ensembl Gene ModelENSMUSG00000064356 (Evidence)
Entrez Gene17706
International Mouse Knockout Project Statusmt-Atp8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000064356 Ensembl Gene Model | MGI Sequence Detail 204 C57BL/6J ±  kb
transcript ENSMUST00000082407 Ensembl | MGI Sequence Detail 204 Not Applicable 
polypeptide ENSMUSP00000080995 Ensembl | MGI Sequence Detail 67 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(1) UniProt(2)
Protein-related
information
ResourceIDDescription
InterPro IPR001421 ATPase, F0 complex, subunit 8, mitochondrial, Metazoan
References (Earliest) J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
(Latest) J:192944 Weiss H, et al., The mitochondrial Atp8 mutation induces mitochondrial ROS generation, secretory dysfunction, and beta-cell mass adaptation in conplastic B6-mtFVB mice. Endocrinology. 2012 Oct;153(10):4666-76
All references(19)
Other
accession IDs
MGD-MRK-16728

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory