mt-Atp8
Gene Detail

Symbol Name ID

mt-Atp8 mitochondrially encoded ATP synthase 8 MGI:99926

Synonyms

URFA6L

Feature Type

protein coding gene

Genetic Map

Chromosome MT
Syntenic

Sequence Map

ChrMT:7766-7969 bp, + strand From Ensembl annotation of GRCm38   204 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5020  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: F-type ATP synthase, subunit 8, animal type
Gene Tree: mt-Atp8

Alleles and phenotypes

All alleles(1) : Spontaneous(1)
 

Mice carrying homoplastic mtDNAs with a single point mutation in this gene exhibit increased anxiety-like behavior.

 

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	ATP biosynthetic process, ATP synthesis coupled proton transport, ...
Component	integral to membrane, membrane, ...
Function	hydrogen ion transmembrane transporter activity, hydrolase activity, ...

Expression

Literature Summary: (1 records)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(52) Other(52)

Other database links

Ensembl Gene Model	ENSMUSG00000064356 (Evidence)
Entrez Gene	17706
International Mouse Knockout Project Status	mt-Atp8

Sequences

Length	Strain/Species
genomic	ENSMUSG00000064356	Ensembl Gene Model | MGI Sequence Detail	204	C57BL/6J
transcript	ENSMUST00000082407	Ensembl | MGI Sequence Detail	204	Not Applicable
polypeptide	ENSMUSP00000080995	Ensembl | MGI Sequence Detail	67	Not Applicable

All sequences(56) RefSeq(1) UniProt(2)

Protein-related information

Resource	ID	Description
InterPro	IPR001421	ATPase, F0 complex, subunit 8, mitochondrial, Metazoan

References

(Earliest) J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
(Latest) J:192944 Weiss H, et al., The mitochondrial Atp8 mutation induces mitochondrial ROS generation, secretory dysfunction, and beta-cell mass adaptation in conplastic B6-mtFVB mice. Endocrinology. 2012 Oct;153(10):4666-76
All references(19)

Other accession IDs

MGD-MRK-16728