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Xist
Gene Detail
 Symbol
Name
ID
Xist
inactive X specific transcripts
MGI:98974
BioType Conflict
Feature Type lincRNA gene
Genetic Map
Chromosome X
46.15 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(62)
Sequence Map
ChrX:103460375-103483217 bp, - strand
From VEGA annotation of GRCm38

  22843 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Xist
Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Targeted(22)
 
Xist function in X-inactivation is disrupted in females carrying a null mutation. Depending on maternal or paternal derivation of the mutation, females survive or die in early embryogenesis. In either case, X-inactivation is non-random and abnormal.
 
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process dosage compensation by inactivation of X chromosome, spongiotrophoblast differentiation
Component chromosome, nucleus
External Resources: FuncBase
Expression
Literature Summary: (50 records)
Data Summary: Results (133)    Tissues (44)    Images (22)
Theiler Stages: 3, 13, 15, 17, 19, 20, 21, 22, 24, 26, 28
Assay TypeResults
RNA in situ 32
Northern blot 4
RT-PCR 95
RNase protection 2
cDNA source data(26)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(146) Genomic(93) cDNA(32) Primer pair(14) Other(7)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000018295 (Evidence)
Ensembl Gene ModelENSMUSG00000086503 (Evidence)
Entrez Gene213742 (Evidence)
International Mouse Knockout Project StatusXist
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018295 VEGA Gene Model | MGI Sequence Detail 22843 C57BL/6J ±  kb
transcript OTTMUST00000044201 VEGA | MGI Sequence Detail 17769 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(2)
Polymorphisms RFLP(5) : SNPs within 2kb(62 from dbSNP Build 137)
References (Earliest) J:2970 Brown SD, XIST and the mapping of the X chromosome inactivation centre. Bioessays. 1991 Nov;13(11):607-12
(Latest) J:206774 Wolstenholme JT, et al., Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes. Genes Brain Behav. 2013 Mar;12(2):166-80
All references(198)
Other
accession IDs
MGD-MRK-15474, MGI:2147863

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory