About   Help   FAQ
Xist
Gene Detail
Symbol

Name
ID
Xist
inactive X specific transcripts
MGI:98974
Feature Type
lincRNA gene
Genetic Map
Chromosome X
46.15 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(62)
Sequence Map
ChrX:103460375-103483217 bp, - strand
From VEGA annotation of GRCm38

  22843 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HCOP human homology predictions: XIST
Gene Tree: Xist
Human
homologs
XIST, X inactive specific transcript (non-protein coding)
Orthology source: HGNC

IDs:
NCBI Gene ID: 7503

Human Synonyms: DXS1089, DXS399E, LINC00001, NCRNA00001, swd66, SXI1

Human Chr (Location): Xq13.2; chrX:73820651-73852753 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Targeted(22)
 
Xist function in X-inactivation is disrupted in females carrying a null mutation. Depending on maternal or paternal derivation of the mutation, females survive or die in early embryogenesis. In either case, X-inactivation is non-random and abnormal.
 
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process dosage compensation by inactivation of X chromosome, spongiotrophoblast differentiation
Component chromosome, nucleus, ...
External Resources: FuncBase
Expression
Literature Summary: (51 records)
Data Summary: Results (140)    Tissues (50)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 32
Northern blot 4
RT-PCR 102
RNase protection 2
cDNA source data(26)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(147) Genomic(93) cDNA(32) Primer pair(15) Other(7)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000018295 (Evidence)
Ensembl Gene Model ENSMUSG00000086503 (Evidence)
Entrez Gene 213742 (Evidence)
International Mouse Phenotyping Consortium Status Xist
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018295 VEGA Gene Model | MGI Sequence Detail 22843 C57BL/6J ±  kb
transcript NR_001463 RefSeq | MGI Sequence Detail 17918 Not Specified 

For the selected sequences
All sequences(36) RefSeq(2)
Polymorphisms
RFLP(5) : SNPs within 2kb(62 from dbSNP Build 137)
References
(Earliest) J:2970 Brown SD, XIST and the mapping of the X chromosome inactivation centre. Bioessays. 1991 Nov;13(11):607-12
(Latest) J:213272 Shin J, et al., RLIM is dispensable for X-chromosome inactivation in the mouse embryonic epiblast. Nature. 2014 Jul 3;511(7507):86-9
All references(201)
Other
accession IDs
MGD-MRK-15474, MGI:2147863

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/18/2015
MGI 6.0
The Jackson Laboratory