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Prss1
Gene Detail
 Symbol
Name
ID
Prss1
protease, serine 1 (trypsin 1)
MGI:98839
Synonyms PRSS1, Try1, Try-1, Trygn16
Feature Type protein coding gene
Genetic Map
Chromosome 6
19.60 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr6:41458932-41463786 bp, + strand
From VEGA annotation of GRCm38

  4855 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:88408  Vertebrate Homology Class
4 mouse; 5 rat

Protein SuperFamily: trypsin
Gene Tree: Prss1

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Prss1 interacts with 10 markers (Mir205, Mir325, Mir342, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process proteolysis
Function hydrolase activity, peptidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (11)    Tissues (1)    Images (11)
Theiler Stages: 23
Assay TypeResults
RNA in situ 11
cDNA source data(1)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000026897 (Evidence)
Ensembl Gene ModelENSMUSG00000062751 (Evidence)
Entrez Gene114228 (Evidence)
EC3.4.21.4
Consensus CDS ProjectCCDS20049.1
International Mouse Knockout Project StatusPrss1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026897 VEGA Gene Model | MGI Sequence Detail 4855 C57BL/6J ±  kb
transcript OTTMUST00000066517 VEGA | MGI Sequence Detail 805 Not Applicable 
polypeptide OTTMUSP00000033342 VEGA | MGI Sequence Detail 246 Not Applicable 

For the selected sequences
All sequences(13) RefSeq(3) UniProt(1)
Polymorphisms RFLP(1) : SNPs within 2kb(56 from dbSNP Build 137)    SNPs within 2kb including multiple locations(96)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
References (Earliest) J:4779 Honey NK, et al., Assignment in mouse of the genes for chymotrypsinogen B, elastase, trypsin, and carboxypeptidase A (Abstracts of meeting presentations: Human gene mapping 7, Los Angeles Conference (1983) Seventh International Workshop on Human Gene Mapping). Cytogenet Cell Genet. 1984;37 (1-4):492-493 (Abstr.) (399-616)
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(25)
Other
accession IDs
MGD-MRK-15253, MGD-MRK-15254, MGI:2148749

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory