Prss1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prss1
serine protease 1 (trypsin 1)
MGI:98839

7 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prss1^{tm1.1(KOMP)Vlcg}/Prss1^{tm1.1(KOMP)Vlcg} C57BL/6N-Prss1^{tm1.1(KOMP)Vlcg}/Ucd	enlarged heart	J:211773
Tg(Ela2a-Prss1,-GFP)1Dbs/0 C57BL/6-Tg(Ela2a-Prss1,-GFP)1Dbs	abnormal pancreatic acinar cell morphology	J:144663
	abnormal pancreatic acinar cell physiology	J:144663
	chronic pancreas inflammation	J:144663
	increased susceptibility to induced pancreatitis	J:144663
	pancreas fibrosis	J:144663
	pancreas necrosis	J:144663

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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