Serpina3m
Gene Detail

Symbol Name ID

Serpina3m serine (or cysteine) peptidase inhibitor, clade A, member 3M MGI:98378

Synonyms

3e46, alpha-1 antiproteinase, antitrypsin, contrapsin-like, MMCM7, MMSPi2.4, Spi2.4, Spi-2l, Spi-2rs1, Spi2-rs1

Feature Type

protein coding gene

Genetic Map

Chromosome 12

54.12 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr12:104387164-104394257 bp, + strand From VEGA annotation of GRCm38   7094 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:40659  Vertebrate Homology Class
3 mouse; 1 rat

Protein SuperFamily: serpin
Gene Tree: Serpina3m

Alleles and phenotypes

All alleles(2) : Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	negative regulation of endopeptidase activity, negative regulation of peptidase activity, ...
Component	extracellular region
Function	peptidase inhibitor activity, serine-type endopeptidase inhibitor activity

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (34)    Tissues (7)    Images (19)
Theiler Stages: 23

Assay Type	Results
RNA in situ	34

cDNA source data(8)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(9) cDNA(9)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000035429 (Evidence)
Ensembl Gene Model	ENSMUSG00000079012 (Evidence)
Entrez Gene	20717 (Evidence)
DoTS	DT.110926991, DT.94135901
Consensus CDS Project	CCDS36538.1
International Mouse Knockout Project Status	Serpina3m

Sequences

Length	Strain/Species
genomic	OTTMUSG00000035429	VEGA Gene Model | MGI Sequence Detail	7094	C57BL/6J
transcript	OTTMUST00000090587	VEGA | MGI Sequence Detail	1659	Not Applicable
polypeptide	OTTMUSP00000049730	VEGA | MGI Sequence Detail	418	Not Applicable

All sequences(22) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(228 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023795	Protease inhibitor I4, serpin, conserved site
InterPro	IPR023796	Serpin domain
InterPro	IPR000215	Serpin family
Protein Ontology	PR:000015939	serine protease inhibitor A3M

References

(Earliest) J:11249 Ohkubo K, et al., Cloning, structure and expression of cDNA for mouse contrapsin and a related protein. Biochem J. 1991 Jun 1;276(Pt 2):337-42
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(27)

Other accession IDs

MGD-MRK-14522, MGD-MRK-14524, MGD-MRK-14527, MGI:2144772