About   Help   FAQ
Sox12
Gene Detail
Symbol

Name
ID
Sox12
SRY (sex determining region Y)-box 12
MGI:98360
Synonyms
2010205A02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 2
74.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:152393611-152398063 bp, - strand
From VEGA annotation of GRCm38

  4453 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5057  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog; 1 chicken

HCOP human homology predictions: SOX12
Protein SuperFamily: SOX-12/11/4a protein
Gene Tree: Sox12

Human
homologs
SOX12, SRY (sex determining region Y)-box 12
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 6666
neXtProt AC: NX_O15370

Human Synonyms: SOX22

Human Chr (Location): 20p13; chr20:325571-330228 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
 
Mice homozygous for a null allele exhibit no phenotypic abnormalities.
 
Interactions
Sox12 interacts with 317 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (13 records)
Data Summary: Results (49)    Tissues (22)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 46
RT-PCR 3
cDNA source data(60)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(62) cDNA(60) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000015843 (Evidence)
Ensembl Gene Model ENSMUSG00000051817 (Evidence)
Entrez Gene 20667 (Evidence)
UniGene 28424
DFCI TC1603705, TC1612934
DoTS DT.101170747, DT.40145331, DT.60102884
Consensus CDS Project CCDS38274.1
International Mouse Phenotyping Consortium Status Sox12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015843 VEGA Gene Model | MGI Sequence Detail 4453 C57BL/6J ±  kb
transcript OTTMUST00000116819 VEGA | MGI Sequence Detail 4453 Not Applicable 
polypeptide OTTMUSP00000065190 VEGA | MGI Sequence Detail 314 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(19 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009071 High mobility group (HMG) box domain
Protein Ontology PR:000015420 transcription factor SOX-12
References
(Earliest) J:4011 Wright EM, et al., Seven new members of the Sox gene family expressed during mouse development. Nucleic Acids Res. 1993 Feb 11;21(3):744
(Latest) J:220744 Xu EE, et al., SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models. Diabetologia. 2015 May;58(5):1013-23
All references(41)
Other
accession IDs
MGD-MRK-14499, MGI:1917235

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/18/2015
MGI 6.0
The Jackson Laboratory