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Sox12
Gene Detail
Symbol

Name
ID
Sox12
SRY (sex determining region Y)-box 12
MGI:98360
Synonyms
2010205A02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 2
74.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:152393611-152398063 bp, - strand
From VEGA annotation of GRCm38

  4453 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5057  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog; 1 chicken

Protein SuperFamily: SOX-12/11/4a protein
Gene Tree: Sox12

Human
homologs
Human Homolog SOX12, SRY (sex determining region Y)-box 12
NCBI Gene ID 6666
neXtProt AC  NX_O15370
Human Synonyms  SOX22
Human Chr (Location)  20p13; chr20:325571-330228 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
 
Mice homozygous for a null allele exhibit no phenotypic abnormalities.
 
Interactions
Sox12 interacts with 317 markers (Mir7-1, Mir7-2, Mir7b, ...)
Expression
Literature Summary: (12 records)
Data Summary: Results (49)    Tissues (22)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 46
RT-PCR 3
cDNA source data(60)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(62) cDNA(60) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000015843 (Evidence)
Ensembl Gene ModelENSMUSG00000051817 (Evidence)
Entrez Gene20667 (Evidence)
UniGene28424
DFCITC1603705, TC1612934
DoTSDT.101170747, DT.40145331, DT.60102884
Consensus CDS ProjectCCDS38274.1
International Mouse Knockout Project StatusSox12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015843 VEGA Gene Model | MGI Sequence Detail 4453 C57BL/6J ±  kb
transcript OTTMUST00000116819 VEGA | MGI Sequence Detail 4453 Not Applicable 
polypeptide OTTMUSP00000065190 VEGA | MGI Sequence Detail 314 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(19 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009071 High mobility group (HMG) box domain
InterPro IPR017386 Transcription factor SOX-12/11/4a
Protein Ontology PR:000015420 transcription factor SOX-12
References
(Earliest) J:4011 Wright EM, et al., Seven new members of the Sox gene family expressed during mouse development. Nucleic Acids Res. 1993 Feb 11;21(3):744
(Latest) J:204578 Gaber ZB, et al., PLZF regulates fibroblast growth factor responsiveness and maintenance of neural progenitors. PLoS Biol. 2013 Oct;11(10):e1001676
All references(41)
Other
accession IDs
MGD-MRK-14499, MGI:1917235

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory