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Snai1
Gene Detail
Symbol

Name
ID
Snai1
snail family zinc finger 1
MGI:98330
Synonyms
Sna, Sna1, Snail, Snail1
Feature Type
protein coding gene
Genetic Map
Chromosome 2
87.33 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:167538195-167542814 bp, + strand
From VEGA annotation of GRCm38

  4620 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4363  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: SNAI1
Gene Tree: Snai1

Human
homologs
SNAI1, snail family zinc finger 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 6615
neXtProt AC: NX_O95863

Human Synonyms: dJ710H13.1, SLUGH2, SNA, SNAH, SNAIL, SNAIL1

Human Chr (Location): 20q13.2; chr20:49982976-49988886 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
 
Mice homozygous for a knock-out allele exhibit lethality by E8.5, reduced size, and abnormal mesoderm development.
 
Interactions
Snai1 interacts with 152 markers (Mir7-2, Mir7b, Mir18, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (48 annotations)
Process cartilage morphogenesis, cell migration, ...
Component cytoplasm, nucleus
Function DNA binding, kinase binding, ...
External Resources: FuncBase
Expression
Literature Summary: (135 records)
Data Summary: Results (681)    Tissues (384)    Images (114)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 2
RNA in situ 654
Northern blot 5
RT-PCR 20
cDNA source data(39)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase snai1 ; ZFIN snai1a, snai1b    NEW 
Molecular
reagents
All nucleic(53) Genomic(1) cDNA(40) Primer pair(6) Other(6)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000001149 (Evidence)
Ensembl Gene Model ENSMUSG00000042821 (Evidence)
Entrez Gene 20613 (Evidence)
UniGene 2093
DFCI TC1578795
DoTS DT.492021
NIA Mouse Gene Index U002851
Consensus CDS Project CCDS17102.1
International Mouse Phenotyping Consortium Status Snai1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001149 VEGA Gene Model | MGI Sequence Detail 4620 C57BL/6J ±  kb
transcript OTTMUST00000002241 VEGA | MGI Sequence Detail 1621 Not Applicable 
polypeptide OTTMUSP00000001090 VEGA | MGI Sequence Detail 264 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(21 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000015308 zinc finger protein SNAI1
References
(Earliest) J:3088 Nieto MA, et al., Cloning and developmental expression of Sna, a murine homologue of the Drosophila snail gene. Development. 1992 Sep;116(1):227-37
(Latest) J:217668 Harikrishnan K, et al., Fibulin-1 suppresses endothelial to mesenchymal transition in the proximal outflow tract. Mech Dev. 2015 Jan 6;
All references(198)
Other
accession IDs
MGD-MRK-14460, MGI:2138858

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory