Snai1
Gene Detail

Symbol Name ID

Snai1 snail homolog 1 (Drosophila) MGI:98330

Synonyms

Sna, Sna1, Snail, Snail1

Feature Type

protein coding gene

Genetic Map

Chromosome 2

87.33 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr2:167538195-167542814 bp, + strand From VEGA annotation of GRCm38   4620 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:4363  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 zebrafish

Gene Tree: Snai1

Human homologs

Human Homolog		SNAI1, snail homolog 1 (Drosophila)
NCBI Gene ID		6615
neXtProt AC		NX_O95863
Human Synonyms		dJ710H13.1, SLUGH2, SNA, SNAH, SNAIL, SNAIL1
Human Chr (Location)		20q13.2; chr20:48599513-48605423 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(5)
 

Mice homozygous for a knock-out allele exhibit lethality by E8.5, reduced size, and abnormal mesoderm development.

 

Gene Ontology (GO) classifications

All GO classifications: (44 annotations)

Process	cartilage morphogenesis, cell migration, ...
Component	cytoplasm, nucleus
Function	DNA binding, kinase binding, ...

External Resources: FuncBase

Expression

Literature Summary: (113 records)
Data Summary: Results (418)    Tissues (296)    Images (98)
Theiler Stages: 2, 3, 4, 5, 9, 10, 11, 12, 13, 15, 17, 19, 20, 21, 22, 23, 24, 25, 26, 28

Assay Type	Results
RNA in situ	392
Northern blot	5
RT-PCR	21

cDNA source data(38)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(49) Genomic(1) cDNA(39) Primer pair(5) Other(4)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000001149 (Evidence)
Ensembl Gene Model	ENSMUSG00000042821 (Evidence)
Entrez Gene	20613 (Evidence)
UniGene	2093
DFCI	TC1578795
DoTS	DT.492021
NIA Mouse Gene Index	U002851
Consensus CDS Project	CCDS17102.1
International Mouse Knockout Project Status	Snai1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000001149	VEGA Gene Model | MGI Sequence Detail	4620	C57BL/6J
transcript	OTTMUST00000002241	VEGA | MGI Sequence Detail	1621	Not Applicable
polypeptide	OTTMUSP00000001090	VEGA | MGI Sequence Detail	264	Not Applicable

All sequences(22) RefSeq(2) UniProt(2)

Polymorphisms

RFLP(1) : SNPs(14 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007087	Zinc finger, C2H2
InterPro	IPR015880	Zinc finger, C2H2-like
InterPro	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology	PR:000015308	zinc finger protein SNAI1

References

(Earliest) J:3088 Nieto MA, et al., Cloning and developmental expression of Sna, a murine homologue of the Drosophila snail gene. Development. 1992 Sep;116(1):227-37
(Latest) J:193689 Takasuga S, et al., Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine. Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1726-31
All references(170)

Other accession IDs

MGD-MRK-14460, MGI:2138858