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Snai1
Gene Detail
 Symbol
Name
ID
Snai1
snail family zinc finger 1
MGI:98330
Synonyms Sna, Sna1, Snail, Snail1
Feature Type protein coding gene
Genetic Map
Chromosome 2
87.33 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:167538195-167542814 bp, + strand
From VEGA annotation of GRCm38

  4620 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4363  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Snai1

Human
homologs
Human Homolog SNAI1, snail family zinc finger 1
NCBI Gene ID 6615
neXtProt AC  NX_O95863
Human Synonyms  dJ710H13.1, SLUGH2, SNA, SNAH, SNAIL, SNAIL1
Human Chr (Location)  20q13.2; chr20:49982976-49988886 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
 
Mice homozygous for a knock-out allele exhibit lethality by E8.5, reduced size, and abnormal mesoderm development.
 
Interactions
Snai1 interacts with 151 markers (Mir7-2, Mir7b, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (47 annotations)
Process cartilage morphogenesis, cell migration, ...
Component cytoplasm, nucleus
Function DNA binding, kinase binding, ...
External Resources: FuncBase
Expression
Literature Summary: (125 records)
Data Summary: Results (673)    Tissues (383)    Images (114)
Theiler Stages: 2, 3, 4, 5, 9, 10, 11, 12, 13, 15, 17, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28
Assay TypeResults
RNA in situ 652
Northern blot 5
RT-PCR 16
cDNA source data(39)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(52) Genomic(1) cDNA(40) Primer pair(6) Other(5)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000001149 (Evidence)
Ensembl Gene ModelENSMUSG00000042821 (Evidence)
Entrez Gene20613 (Evidence)
UniGene2093
DFCITC1578795
DoTSDT.492021
NIA Mouse Gene IndexU002851
Consensus CDS ProjectCCDS17102.1
International Mouse Knockout Project StatusSnai1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001149 VEGA Gene Model | MGI Sequence Detail 4620 C57BL/6J ±  kb
transcript OTTMUST00000002241 VEGA | MGI Sequence Detail 1621 Not Applicable 
polypeptide OTTMUSP00000001090 VEGA | MGI Sequence Detail 264 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(2)
Polymorphisms RFLP(1) : SNPs within 2kb(21 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000015308 zinc finger protein SNAI1
References (Earliest) J:3088 Nieto MA, et al., Cloning and developmental expression of Sna, a murine homologue of the Drosophila snail gene. Development. 1992 Sep;116(1):227-37
(Latest) J:209623 Kurosaka H, et al., Disrupting hedgehog and WNT signaling interactions promotes cleft lip pathogenesis. J Clin Invest. 2014 Apr 1;124(4):1660-71
All references(189)
Other
accession IDs
MGD-MRK-14460, MGI:2138858

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory