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Gene Detail
complement component 4A (Rodgers blood group)
BioType Conflict
Synonyms Slp
Feature Type protein coding gene
Genetic Map
Chromosome 17
18.37 cM
Detailed Genetic Map ± 1 cM

Mapping data(12)
Sequence Map
Chr17:34809092-34823464 bp, - strand
From VEGA annotation of GRCm38

  14373 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
HomoloGene:36030  Vertebrate Homology Class
2 human; 2 mouse; 2 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: alpha-2-macroglobulin
Gene Tree: C4a

Human Homolog C4A, complement component 4A (Rodgers blood group)
NCBI Gene ID 720
neXtProt AC  NX_P0C0L4
Human Synonyms  C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG
Human Chr (Location)  6p21.3; chr6:31982057-32002680 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human C4A
Human Homolog C4B, complement component 4B (Chido blood group)
NCBI Gene ID 721
neXtProt AC  NX_P0C0L4, NX_P0C0L5
Human Synonyms  C4B1, C4B12, C4B2, C4B_2, C4B3, C4B5, C4BD, C4F, CH, CO4, CPAMD3
Human Chr (Location)  6p21.3; chr6:32014795-32035418 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human C4B
Gene Ontology
All GO classifications: (14 annotations)
Process complement activation
Component blood microparticle, extracellular region, ...
Function carbohydrate binding, complement binding, ...
External Resources: FuncBase
cDNA source data(7)
External Resources: GEO   Expression Atlas
All nucleic(87) Genomic(71) cDNA(14) Other(2)
Microarray probesets(2)
Other database
VEGA Gene ModelOTTMUSG00000033087 (Evidence)
Ensembl Gene ModelENSMUSG00000015451 (Evidence)
Entrez Gene625018 (Evidence)
International Mouse Knockout Project StatusC4a
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033087 VEGA Gene Model | MGI Sequence Detail 14373 C57BL/6J ±  kb
transcript OTTMUST00000082646 VEGA | MGI Sequence Detail 5371 Not Applicable 
polypeptide NP_035543 RefSeq | MGI Sequence Detail 1735 Not Specified 

For the selected sequences
All sequences(53) RefSeq(2)
Polymorphisms RFLP(1) : SNPs within 2kb(237 from dbSNP Build 137)    SNPs within 2kb including multiple locations(421)
References (Earliest) J:5181 Passmore HC, et al., A sex-limited serum protein variant in the mouse: inheritance and association with the H-2 region. Biochem Genet. 1970 Jun;4(3):351-65
(Latest) J:86324 Krebs CJ, et al., Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression. Genes Dev. 2003 Nov 1;17(21):2664-74
All references(67)
accession IDs

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.19
The Jackson Laboratory