About   Help   FAQ
C4a Gene Detail
Summary
  • Symbol
    C4a
  • Name
    complement component 4A (Rodgers blood group)
  • Synonyms
    Slp
Location &
Maps
more
  • Sequence Map
    Chr17:34809092-34823454 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.37 cM
  • Mapping Data
    12 experiments
Strain
Comparison
more
  • Strain Annotations
    7
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98320
protein coding gene Chr17:34809092-34823464 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015350
unclassified non-coding RNA gene Chr17:34826626-34933666 (-)
A/J no annotation
AKR/J MGP_AKRJ_G0015288
unclassified non-coding RNA gene Chr17:34058869-34244791 (-)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0013483
unclassified non-coding RNA gene Chr17:31527032-31542709 (-)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0015266
unclassified non-coding RNA gene Chr17:35211346-35240269 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015219
unclassified non-coding RNA gene Chr17:36520117-36521624 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0014770
unclassified non-coding RNA gene Chr17:34478931-34496289 (-)



Homology
more
  • Human Ortholog
    C4A, complement C4A (Rodgers blood group)
  • Vertebrate Orthologs
    12
  • Human Ortholog
    C4A, complement C4A (Rodgers blood group)
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG
  • Links
    NCBI Gene ID: 720
    neXtProt AC: NX_P0C0L4
    UniProt: P0C0L4

  • Chr Location
    6p21.33; chr6:31982057-32002680 (+)  GRCh38.p7

  • Human Ortholog
    C4B, complement C4B (Chido blood group)
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C4B1, C4B12, C4B2, C4B_2, C4B3, C4B5, C4BD, C4F, CH, CO4, CPAMD3
  • Links
    NCBI Gene ID: 721
    neXtProt AC: NX_P0C0L4, NX_P0C0L5
    UniProt: P0C0L5

  • Chr Location
    6p21.33; chr6:32014795-32035418 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    2 with human C4A,C4B associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 625018 NCBI Gene Model | MGI Sequence Detail 14363 C57BL/6J ±  kb
transcript NM_011413 RefSeq | MGI Sequence Detail 5369 Not Specified  
polypeptide NP_035543 RefSeq | MGI Sequence Detail 1735 Not Specified  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 87
    Genomic 71
    cDNA 14
    Other 2

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-14443
References
more
  • Summaries
    All 67
    Gene Ontology 5
  • Earliest
    J:5181 Passmore HC, et al., A sex-limited serum protein variant in the mouse: inheritance and association with the H-2 region. Biochem Genet. 1970 Jun;4(3):351-65
  • Latest
    J:229241 Sekar A, et al., Schizophrenia risk from complex variation of complement component 4. Nature. 2016 Feb 11;530(7589):177-83

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/11/2018
MGI 6.13
The Jackson Laboratory