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C4a
Gene Detail
Symbol

Name
ID
C4a
complement component 4A (Rodgers blood group)
MGI:98320
Synonyms
Slp
Feature Type
protein coding gene
Genetic Map
Chromosome 17
18.37 cM
Detailed Genetic Map ± 1 cM


Mapping data(12)
Sequence Map
Chr17:34809092-34823464 bp, - strand
From VEGA annotation of GRCm38

  14373 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36030  Vertebrate Homology Class
2 human; 2 mouse; 2 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: alpha-2-macroglobulin
Gene Tree: C4a

Human
homologs
Human Homolog C4A, complement component 4A (Rodgers blood group)
NCBI Gene ID 720
neXtProt AC  NX_P0C0L4
Human Synonyms  C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG
Human Chr (Location)  6p21.3; chr6:31982057-32002680 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human C4A
Human Homolog C4B, complement component 4B (Chido blood group)
NCBI Gene ID 721
neXtProt AC  NX_P0C0L4, NX_P0C0L5
Human Synonyms  C4B1, C4B12, C4B2, C4B_2, C4B3, C4B5, C4BD, C4F, CH, CO4, CPAMD3
Human Chr (Location)  6p21.3; chr6:32014795-32035418 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human C4B
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process complement activation
Component blood microparticle, extracellular region, ...
Function carbohydrate binding, complement binding, ...
External Resources: FuncBase
Expression
cDNA source data(7)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(87) Genomic(71) cDNA(14) Other(2)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000033087 (Evidence)
Ensembl Gene ModelENSMUSG00000015451 (Evidence)
Entrez Gene625018 (Evidence)
International Mouse Knockout Project StatusC4a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033087 VEGA Gene Model | MGI Sequence Detail 14373 C57BL/6J ±  kb
transcript OTTMUST00000082646 VEGA | MGI Sequence Detail 5371 Not Applicable 
polypeptide NP_035543 RefSeq | MGI Sequence Detail 1735 Not Specified 

For the selected sequences
All sequences(53) RefSeq(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(237 from dbSNP Build 137)    SNPs within 2kb including multiple locations(421)
References
(Earliest) J:5181 Passmore HC, et al., A sex-limited serum protein variant in the mouse: inheritance and association with the H-2 region. Biochem Genet. 1970 Jun;4(3):351-65
(Latest) J:86324 Krebs CJ, et al., Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression. Genes Dev. 2003 Nov 1;17(21):2664-74
All references(67)
Other
accession IDs
MGD-MRK-14443

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory