Sequence Detail

ID/Version

A0AAQ4VMX2 B9EIU2 Q6P3Y0 V9GZG9 (UniProt | EBI)

Last sequence update: 2024-10-02
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Complement C4-A;AltName: Full=Sex-limited protein {ECO:0000303|PubMed:6208559};Contains: RecName: Full=Complement C4 beta chain;Contains: RecName: Full=Complement C4-A alpha chain;Contains: RecName: Full=C4a anaphylatoxin;Contains: RecNa

Provider

SWISS-PROT

Sequence

Polypeptide 1734 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	C4a	complement C4A (Rodgers blood group)	16	96	2	0

Sequence references in MGI

J:7633 Nonaka M, et al., Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein. Proc Natl Acad Sci U S A. 1984 Nov;81(21):6822-6
J:8067 Nonaka M, et al., Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp. Immunol Rev. 1985 Oct;87:81-99
J:18023 Van den Berg CW, et al., Rapid, activity-guided isolation of sex-limited protein (Slp) from mouse serum by fractionated precipitation and high-performance liquid chromatography. J Immunol Methods. 1994 Mar 10;169(2):251-6
J:301513 Zarantonello A, et al., An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase. J Immunol. 2020 Sep 15;205(6):1678-1694