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Rlbp1 Gene Detail
Summary
  • Symbol
    Rlbp1
  • Name
    retinaldehyde binding protein 1
  • Synonyms
    3110056M11Rik, CRALBP
  • Feature Type
    protein coding gene
  • IDs
    MGI:97930
    NCBI Gene: 19771
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:79024618-79036796 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 45.00 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    414 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97930
 protein coding gene Chr7:79024613-79041989 (-)
129S1/SvImJ ENSMUSG00200034395
 protein coding gene Chr7:65837687-65850166 (-)
A/J ENSMUSG00195013440
 protein coding gene Chr7:70253276-70265462 (-)
AKR/J ENSMUSG00220036105
 protein coding gene Chr7:63795290-63807481 (-)
BALB/cJ ENSMUSG00180013181
 protein coding gene Chr7:66978391-66990574 (-)
C3H/HeJ ENSMUSG00175020737
 protein coding gene Chr7:67749765-67762242 (-)
C57BL/6NJ ENSMUSG00215014241
 protein coding gene Chr7:66849409-66861586 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029878
 protein coding gene Chr7:81924705-81937228 (-)
CAST/EiJ ENSTCUG00005003929
 protein coding gene Chr7:70300891-70312937 (-)
CBA/J ENSMUSG00210023819
 protein coding gene Chr7:67601053-67613529 (-)
DBA/2J ENSMUSG00185044920
 protein coding gene Chr7:71923769-71936261 (-)
FVB/NJ ENSMUSG00205021920
 protein coding gene Chr7:67490259-67502447 (-)
JF1/MsJ ENSUMUG00000009387
 protein coding gene Chr7:76583404-76595955 (-)
LP/J ENSMUSG00230011028
 protein coding gene Chr7:78014064-78026250 (-)
NOD/ShiLtJ ENSMUSG00190018119
 protein coding gene Chr7:67742997-67755183 (-)
NZO/HlLtJ ENSMUSG00225041113
 protein coding gene Chr7:76255375-76267816 (-)
PWK/PhJ ENSLUMG00010016489
 protein coding gene Chr7:66171925-66184102 (-)
SPRET/EiJ ENSMSPG00010021822
 protein coding gene Chr7:66590807-66603060 (-)
WSB/EiJ ENSIUOG00005020175
 protein coding gene Chr7:68091574-68104020 (-)



Homology
more
  • Human Ortholog
    RLBP1, retinaldehyde binding protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RLBP1, retinaldehyde binding protein 1
  • Synonyms
    CRALBP
  • Links
    NCBI Gene ID: 6017
    UniProt: P12271

  • Chr Location
    15q26.1; chr15:89209869-89222577 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Rlbp1 mouse models; 5 with human RLBP1 associations

Human Disease Mouse Models
      
IDs
 View 1 model
      
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    35 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene display delayed dark adaptation as well as reduced retinal degeneration.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    748
  • Tissues
    49
  • cDNA Data
    31
  • Literature Summary
    46
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039194 Ensembl Gene Model | MGI Sequence Detail 12179 C57BL/6J ±  kb
    transcript ENSMUST00000179243 Ensembl | MGI Sequence Detail 2142 Not Applicable  
    polypeptide ENSMUSP00000137143 Ensembl | MGI Sequence Detail 317 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 39
      cDNA 32
      Primer pair 3
      Other 4
      Antibodies 5

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-13896, MGI:1920482
    References
    more
    • Summaries
      All 111
      Developmental Gene Expression 46
      Diseases 1
      Gene Ontology 6
      Phenotypes 35
    • Earliest
      J:6901 Saari JC, et al., Identification of the endogenous retinoids associated with three cellular retinoid-binding proteins from bovine retina and retinal pigment epithelium. J Biol Chem. 1982 Nov 25;257(22):13329-33
    • Latest
      J:390324 Hess C, et al., A Unified Developmental Timeline of Pigmented Ocular Tissues in the Mouse Eye. Exp Eye Res. 2026 Jul 22;:111178
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory