Rab1
Gene Detail

Symbol Name ID

Rab1 RAB1, member RAS oncogene family MGI:97842

Synonyms

Gtbp, mKIAA3012, Rab-1, Rab1A, ras-related YPT1 protein, Ypt1

Feature Type

protein coding gene

Genetic Map

Chromosome 11

12.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(10)

Sequence Map

Chr11:20201432-20226856 bp, + strand From VEGA annotation of GRCm38   25425 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:36154  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab1

Human homologs

Human Homolog		RAB1A, RAB1A, member RAS oncogene family
NCBI Gene ID		5861
neXtProt AC		NX_P62820
Human Synonyms		RAB1, YPT1
Human Chr (Location)		2p14; chr2:65313988-65357435 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(61) : Targeted(3) Gene trapped(58)

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	ER to Golgi vesicle-mediated transport, intracellular protein transport, ...
Component	endoplasmic reticulum, endoplasmic reticulum membrane, ...
Function	GTP binding, nucleotide binding

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (25)    Tissues (16)    Images (3)
Theiler Stages: 23

Assay Type	Results
RNA in situ	25

cDNA source data(16)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(26) Genomic(5) cDNA(19) Primer pair(2)
Microarray probesets(7)

Other database links

VEGA Gene Model	OTTMUSG00000005223 (Evidence)
Ensembl Gene Model	ENSMUSG00000020149 (Evidence)
Entrez Gene	19324 (Evidence)
Consensus CDS Project	CCDS36115.1
International Mouse Knockout Project Status	Rab1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000005223	VEGA Gene Model | MGI Sequence Detail	25425	C57BL/6J
transcript	OTTMUST00000011651	VEGA | MGI Sequence Detail	2827	Not Applicable
polypeptide	OTTMUSP00000005406	VEGA | MGI Sequence Detail	202	Not Applicable

All sequences(82) RefSeq(2) UniProt(7)

Polymorphisms

RFLP(2) : SNPs(111 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR003579	Small GTPase superfamily, Rab type
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000013591	ras-related protein Rab-1A

References

(Earliest) J:20233 Capon DJ, et al., Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue. Nature. 1983 Mar 3;302(5903):33-7
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(60)

Other accession IDs

MGD-MRK-10329, MGD-MRK-13744, MGD-MRK-13745, MGD-MRK-15847