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Rab1a Gene Detail
Summary
  • Symbol
    Rab1a
  • Name
    RAB1A, member RAS oncogene family
  • Synonyms
    Gtbp, mKIAA3012, Rab1, Rab-1, ras-related YPT1 protein, Ypt1
  • Feature Type
    protein coding gene
  • IDs
    MGI:97842
    NCBI Gene: 19324
  • Gene Overview
    MyGene.info: RAB1A
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:20201602-20226856 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 12.92 cM
  • Mapping Data
    10 experiments
Strain
Comparison
more
  • SNPs within 2kb
    147 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97842
protein coding gene Chr11:20201432-20226856 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018064
protein coding gene Chr11:17698616-17727413 (+)
A/J MGP_AJ_G0018037
protein coding gene Chr11:17122901-17148566 (+)
AKR/J MGP_AKRJ_G0018001
protein coding gene Chr11:17728805-17755194 (+)
BALB/cJ MGP_BALBcJ_G0018005
protein coding gene Chr11:17237712-17264592 (+)
C3H/HeJ MGP_C3HHeJ_G0017819
protein coding gene Chr11:17617626-17642827 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018457
protein coding gene Chr11:18507970-18535929 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016115
protein coding gene Chr11:16107010-16130078 (+)
CAST/EiJ MGP_CASTEiJ_G0017380
protein coding gene Chr11:17584164-17609979 (+)
CBA/J MGP_CBAJ_G0017793
protein coding gene Chr11:19320256-19353175 (+)
DBA/2J MGP_DBA2J_G0017903
protein coding gene Chr11:17068293-17093631 (+)
FVB/NJ MGP_FVBNJ_G0017895
protein coding gene Chr11:16806109-16831248 (+)
LP/J MGP_LPJ_G0017974
protein coding gene Chr11:17885100-17910493 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017921
protein coding gene Chr11:19764846-19790997 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018498
protein coding gene Chr11:17806246-17833641 (+)
PWK/PhJ MGP_PWKPhJ_G0017160
protein coding gene Chr11:17074995-17099207 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016958
protein coding gene Chr11:17535102-17562070 (+)
WSB/EiJ MGP_WSBEiJ_G0017434
protein coding gene Chr11:17470434-17496337 (+)



Homology
more
  • Human Ortholog
    RAB1A, RAB1A, member RAS oncogene family
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RAB1A, RAB1A, member RAS oncogene family
    Orthology source: HGNC, HomoloGene
  • Synonyms
    RAB1, YPT1
  • Links
    NCBI Gene ID: 5861
    neXtProt AC: NX_P62820
    UniProt: P62820

  • Chr Location
    2p14; chr2:65086854-65130301 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with Rab1a mouse models

Human Disease Mouse Models
      
IDs
View 3 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    3 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 3 alleles in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 19324 NCBI Gene Model | MGI Sequence Detail 25255 C57BL/6J ±  kb
    transcript NM_008996 RefSeq | MGI Sequence Detail 2871 C57BL/6  
    polypeptide P62821 UniProt | EBI | MGI Sequence Detail 205 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 29
      Genomic 5
      cDNA 21
      Primer pair 2
      Other 1

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGD-MRK-10329, MGD-MRK-13744, MGD-MRK-13745, MGD-MRK-15847
    References
    more
    • Summaries
      All 70
      Developmental Gene Expression 5
      Diseases 1
      Gene Ontology 10
      Phenotypes 14
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:213512 Werber M, et al., The tissue-specific transcriptomic landscape of the mid-gestational mouse embryo. Development. 2014 Jun;141(11):2325-30

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    12/04/2018
    MGI 6.13
    The Jackson Laboratory