About   Help   FAQ
Rab1
Gene Detail
Symbol

Name
ID
Rab1
RAB1, member RAS oncogene family
MGI:97842
Synonyms
Gtbp, mKIAA3012, Rab-1, Rab1A, ras-related YPT1 protein, Ypt1
Feature Type
protein coding gene
Genetic Map
Chromosome 11
12.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(10)
Sequence Map
Chr11:20201432-20226856 bp, + strand
From VEGA annotation of GRCm38

  25425 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36154  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab1

Human
homologs
Human Homolog RAB1A, RAB1A, member RAS oncogene family
NCBI Gene ID 5861
neXtProt AC  NX_P62820
Human Synonyms  RAB1, YPT1
Human Chr (Location)  2p14; chr2:65086854-65130301 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(61) : Gene trapped(58) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rab1 interacts with 364 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (52 annotations)
Process autophagic vacuole assembly, autophagy, ...
Component cell, cytoplasm, ...
Function GDP binding, GTPase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (25)    Tissues (16)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 25
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(26) Genomic(5) cDNA(19) Primer pair(2)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000005223 (Evidence)
Ensembl Gene ModelENSMUSG00000020149 (Evidence)
Entrez Gene19324 (Evidence)
Consensus CDS ProjectCCDS36115.1
International Mouse Knockout Project StatusRab1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005223 VEGA Gene Model | MGI Sequence Detail 25425 C57BL/6J ±  kb
transcript OTTMUST00000011651 VEGA | MGI Sequence Detail 2827 Not Applicable 
polypeptide OTTMUSP00000005406 VEGA | MGI Sequence Detail 202 Not Applicable 

For the selected sequences
All sequences(88) RefSeq(2) UniProt(13)
Polymorphisms
RFLP(2) : SNPs within 2kb(147 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013591 ras-related protein Rab-1A
References
(Earliest) J:20233 Capon DJ, et al., Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue. Nature. 1983 Mar 3;302(5903):33-7
(Latest) J:213512 Werber M, et al., The tissue-specific transcriptomic landscape of the mid-gestational mouse embryo. Development. 2014 Jun;141(11):2325-30
All references(67)
Other
accession IDs
MGD-MRK-10329, MGD-MRK-13744, MGD-MRK-13745, MGD-MRK-15847

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/16/2014
MGI 5.20
The Jackson Laboratory