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Rab1a Gene Detail
Summary
  • Symbol
    Rab1a
  • Name
    RAB1A, member RAS oncogene family
  • Synonyms
    Gtbp, mKIAA3012, Rab1, Rab-1, ras-related YPT1 protein, Ypt1
  • Feature Type
    protein coding gene
  • IDs
    MGI:97842
    NCBI Gene: 19324
  • Gene Overview
    MyGene.info: RAB1A
Location & Maps
more
  • Sequence Map
    Chr11:20201432-20226856 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      25425 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    RAB1A, RAB1A, member RAS oncogene family
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RAB1A, RAB1A, member RAS oncogene family
    Orthology source: HGNC, HomoloGene
  • Synonyms
    RAB1, YPT1
  • Links
    NCBI Gene ID: 5861
    neXtProt AC: NX_P62820

  • Chr Location
    2p14; chr2:65086854-65130301 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    62
  • Chemically induced (other)
    1
  • Gene trapped
    58
  • Targeted
    3
  • Genomic Mutations
    1 involving Rab1a
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005223 VEGA Gene Model | MGI Sequence Detail 25425 C57BL/6J ±  kb
transcript OTTMUST00000011651 VEGA | MGI Sequence Detail 2827 Not Applicable  
polypeptide OTTMUSP00000005406 VEGA | MGI Sequence Detail 202 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    147 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000013591 ras-related protein Rab-1A
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR001806 Small GTPase superfamily
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
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  • All nucleic 26
    Genomic 5
    cDNA 19
    Primer pair 2

    Microarray probesets 7
Other
Accession IDs
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MGD-MRK-10329, MGD-MRK-13744, MGD-MRK-13745, MGD-MRK-15847
References
more
  • Summaries
    All 66
    Developmental Gene Expression 5
    Gene Ontology 10
    Phenotypes 12
  • Earliest
    J:20233 Capon DJ, et al., Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue. Nature. 1983 Mar 3;302(5903):33-7
  • Latest
    J:213512 Werber M, et al., The tissue-specific transcriptomic landscape of the mid-gestational mouse embryo. Development. 2014 Jun;141(11):2325-30

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory