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Pvt1 Gene Detail
Summary
  • Symbol
    Pvt1
  • Name
    Pvt1 oncogene
  • Synonyms
    Ayu21-84Imeg, Gt(Ayu21)84Imeg, Mis-1, Mlvi-1, Pvt-1
Location &
Maps
more
  • Sequence Map
    Chr15:61909835-62132064 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 26.24 cM, cytoband D2-D3
  • Mapping Data
    23 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6018 from dbSNP Build 142
  • Strain Annotations
    31
  • RFLP
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97824
 lncRNA gene Chr15:61888639-62249945 (+)
129S1/SvImJ ENSMUSG00200029541
 lncRNA gene Chr15:58942453-59282695 (+)
129S1/SvImJ ENSMUSG00200028678
 protein coding gene Chr15:58942488-59155723 (+)
A/J ENSMUSG00195005756
 protein coding gene Chr15:58970901-59184141 (+)
A/J ENSMUSG00195006417
 lncRNA gene Chr15:58970866-59311134 (+)
AKR/J ENSMUSG00220020913
 lncRNA gene Chr15:58881137-59221425 (+)
AKR/J ENSMUSG00220020134
 protein coding gene Chr15:58881172-59094442 (+)
BALB/cJ ENSMUSG00180008385
 protein coding gene Chr15:58879907-59096794 (+)
BALB/cJ ENSMUSG00180009649
 lncRNA gene Chr15:58879872-59223736 (+)
C3H/HeJ ENSMUSG00175004565
 protein coding gene Chr15:59171209-59388150 (+)
C3H/HeJ ENSMUSG00175004920
 lncRNA gene Chr15:59171245-59515089 (+)
C57BL/6NJ ENSMUSG00215013829
 lncRNA gene Chr15:58891928-59232192 (+)
C57BL/6NJ ENSMUSG00215011634
 protein coding gene Chr15:58891892-59105218 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0005092
 lincRNA gene Chr15:56055554-56396857 (+)
CAST/EiJ ENSTCUG00005007080
 lncRNA gene Chr15:58720258-59057095 (+)
CBA/J ENSMUSG00210007304
 lncRNA gene Chr15:59002978-59346794 (+)
CBA/J ENSMUSG00210007131
 protein coding gene Chr15:59002942-59219875 (+)
DBA/2J ENSMUSG00185025635
 protein coding gene Chr15:58940622-59153882 (+)
DBA/2J ENSMUSG00185027365
 lncRNA gene Chr15:58940587-59280870 (+)
FVB/NJ ENSMUSG00205006244
 protein coding gene Chr15:58701959-58915231 (+)
FVB/NJ ENSMUSG00205006909
 lncRNA gene Chr15:58701924-59042245 (+)
JF1/MsJ ENSUMUG00000034000
 lncRNA gene Chr15:58708165-59047542 (+)
LP/J ENSMUSG00230026034
 lncRNA gene Chr15:62268026-62608238 (+)
LP/J ENSMUSG00230024045
 protein coding gene Chr15:62267990-62481282 (+)
NOD/ShiLtJ ENSMUSG00190017291
 lncRNA gene Chr15:59531419-59871383 (-)
NOD/ShiLtJ ENSMUSG00190016371
 protein coding gene Chr15:59650247-59871419 (-)
NZO/HlLtJ ENSMUSG00225027346
 lncRNA gene Chr15:62547725-62887977 (+)
NZO/HlLtJ ENSMUSG00225027029
 protein coding gene Chr15:62547721-62760986 (+)
PWK/PhJ ENSLUMG00010029278
 lncRNA gene Chr15:59002920-59340594 (+)
SPRET/EiJ ENSMSPG00010025769
 lncRNA gene Chr15:60292680-60648551 (+)
WSB/EiJ ENSIUOG00005006818
 lncRNA gene Chr15:58988162-59336871 (+)



Homology
more
  • Human Ortholog
    PVT1, Pvt1 oncogene
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PVT1, Pvt1 oncogene
  • Synonyms
    LINC00079, MIR1204HG, NCRNA00079, onco-lncRNA-100, TP53LC09
  • Links
    NCBI Gene ID: 5820

  • Chr Location
    8q24.21; chr8:127794513-128188202 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human PVT1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    38 phenotype references
  • All Mutations and Alleles
    235
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    2
  • Gene trapped
    227
  • Radiation induced
    2
  • Transposon induced
    1
  • Genomic Mutations
    6 involving Pvt1
  • Find Mice (IMSR)
    200 strains or lines available
10-25% of B-cell plasmacytomas have (6;15) translocations that bring Myc into proximity with Igk. The Chr 15 breakpoint occurs at Pvt1, located >72 kb distal to Myc. These tumors have an activated Myc. In addition, some T-cell lymphomas have been shown to have proviral inserts at the Pvt1 locus.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    35
  • Literature Summary
    3
Sequences &
Gene Models
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  • All Sequences
    621
  • RefSeq
    12
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic 19296 NCBI Gene Model | MGI Sequence Detail 222230 C57BL/6J ±  kb
transcript NR_202088 RefSeq | MGI Sequence Detail 3338 C57BL/6  
polypeptide Q3UMI8 UniProt | EBI | MGI Sequence Detail 76 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
Molecular
Reagents
less
  • All nucleic 63
    Genomic 22
    cDNA 39
    Other 2

    Microarray probesets 6
Other
Accession IDs
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MGD-MRK-12245, MGD-MRK-12267, MGD-MRK-13696, MGD-MRK-13697, MGI:3629704
References
more
  • Summaries
    All 98
    Developmental Gene Expression 3
    Diseases 1
    Phenotypes 38
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory