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Phkb
Gene Detail
 Symbol
Name
ID
Phkb
phosphorylase kinase beta
MGI:97578
Synonyms MGC:62514
Feature Type protein coding gene
Genetic Map
Chromosome 8
41.61 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:85840959-86061376 bp, + strand
From VEGA annotation of GRCm38

  220418 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:247  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: phosphorylase b kinase, regulatory beta subunit
Gene Tree: Phkb

Human
homologs
Human Homolog PHKB, phosphorylase kinase, beta
NCBI Gene ID 5257
neXtProt AC  NX_Q93100
Human Chr (Location)  16q12-q13; chr16:47461299-47701523 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human PHKB
Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Gene trapped(14) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Phkb interacts with 288 markers (Mir7-2, Mir7b, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process carbohydrate metabolic process, glycogen metabolic process, ...
Component membrane, phosphorylase kinase complex, ...
Function calmodulin binding, catalytic activity, ...
External Resources: FuncBase
Expression
cDNA source data(89)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(90) cDNA(90)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000031187 (Evidence)
Ensembl Gene ModelENSMUSG00000036879 (Evidence)
Entrez Gene102093 (Evidence)
UniGene237296
DFCITC1578378, TC1612391
DoTSDT.101137330, DT.101254490, DT.97335283, DT.97393850, DT.99685878
NIA Mouse Gene IndexU009605
Consensus CDS ProjectCCDS22501.1
International Mouse Knockout Project StatusPhkb
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031187 VEGA Gene Model | MGI Sequence Detail 220418 C57BL/6J ±  kb
transcript OTTMUST00000077272 VEGA | MGI Sequence Detail 5351 Not Applicable 
polypeptide OTTMUSP00000040826 VEGA | MGI Sequence Detail 1085 Not Applicable 

For the selected sequences
All sequences(88) RefSeq(24) UniProt(10)
Polymorphisms RFLP(2) : SNPs within 2kb(1354 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011613 Glycoside hydrolase family 15
InterPro IPR008734 Phosphorylase kinase alpha/beta subunit
InterPro IPR008928 Six-hairpin glycosidase-like
Protein Ontology PR:000012660 phosphorylase b kinase regulatory subunit beta
References (Earliest) J:8697 Chamberlain JS, et al., Isolation of cDNA clones for the catalytic gamma subunit of mouse muscle phosphorylase kinase: expression of mRNA in normal and mutant Phk mice. Proc Natl Acad Sci U S A. 1987 May;84(9):2886-90
(Latest) J:186636 Arun G, et al., mrhl RNA, a Long Noncoding RNA, Negatively Regulates Wnt Signaling through Its Protein Partner Ddx5/p68 in Mouse Spermatogonial Cells. Mol Cell Biol. 2012 Aug;32(15):3140-52
All references(41)
Other
accession IDs
MGD-MRK-13297, MGI:2142562

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory