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Pecam1
Gene Detail
 Symbol
Name
ID
Pecam1
platelet/endothelial cell adhesion molecule 1
MGI:97537
Synonyms Cd31, PECAM-1
Feature Type protein coding gene
Genetic Map
Chromosome 11
69.92 cM, cytoband F3-G1
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr11:106654217-106750628 bp, - strand
From VEGA annotation of GRCm38

  96412 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:47925  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Pecam1

Human
homologs
Human Homolog PECAM1, platelet/endothelial cell adhesion molecule 1
NCBI Gene ID 5175
neXtProt AC  NX_P16284
Human Synonyms  CD31, CD31/EndoCAM, endoCAM, GPIIA', PECA1, PECAM-1
Human Chr (Location)  17q23.3; chr17:64319415-64413779 (-)  GRCh38
Alleles
and
phenotypes
All alleles(451) : Gene trapped(449) Targeted(2)
Incidental mutations (data from APF )
 
Mice homozygous for a knock-out allele show increased susceptibility to collagen-induced arthritis, impaired lung alveolarization, and enhanced susceptibility to endotoxic shock. Mice homozygous for a gene-trapped allele show altered vasodilation and nitric oxide homeostasis.
 
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process cell adhesion, cellular component movement, ...
Component cell junction, cell periphery, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (1155 records)
Data Summary: Results (1121)    Tissues (315)    Images (715)
Theiler Stages: 2, 3, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
Immunohistochemistry 866
RNA in situ 145
Northern blot 6
Western blot 16
RT-PCR 88
cDNA source data(114)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(127) Genomic(2) cDNA(114) Primer pair(10) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000003418 (Evidence)
Ensembl Gene ModelENSMUSG00000020717 (Evidence)
Entrez Gene18613 (Evidence)
UniGene343951
DFCITC1575759, TC1590099, TC1626565, TC1642275
DoTSDT.101712762, DT.528306, DT.534741, DT.91288847, DT.94313019, DT.94380327, DT.97342919
NIA Mouse Gene IndexU033547
Consensus CDS ProjectCCDS25558.1, CCDS25559.1
International Mouse Knockout Project StatusPecam1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003418 VEGA Gene Model | MGI Sequence Detail 96412 C57BL/6J ±  kb
transcript OTTMUST00000007192 VEGA | MGI Sequence Detail 2977 Not Applicable 
polypeptide OTTMUSP00000003453 VEGA | MGI Sequence Detail 732 Not Applicable 

For the selected sequences
All sequences(84) RefSeq(24) UniProt(4)
Polymorphisms SNPs within 2kb(329 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
Protein Ontology PR:000001904 platelet endothelial cell adhesion molecule
References (Earliest) J:2787 Bogen SA, et al., Association of murine CD31 with transmigrating lymphocytes following antigenic stimulation. Am J Pathol. 1992 Oct;141(4):843-54
(Latest) J:206581 Bowles J, et al., Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo. Dev Biol. 2014 Feb 1;386(1):25-33
All references(1303)
Other
accession IDs
MGD-MRK-13226, MGD-MRK-1848, MGI:2144682

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory