Pecam1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pecam1
platelet/endothelial cell adhesion molecule 1
MGI:97537

21 phenotypes from 2 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pecam1^{Gt(OST16303)Lex}/Pecam1^{Gt(OST16303)Lex} B6.129S5-Pecam1^{Gt(OST16303)Lex}	abnormal nitric oxide homeostasis	J:104082
	decreased vasodilation	J:104082
Pecam1^{Gt(OST16303)Lex}/Pecam1^{Gt(OST16303)Lex} B6.129S-Pecam1^{Gt(OST16303)Lex}/J	abnormal vasodilation	J:114343
	decreased vasodilation	J:114343
Pecam1^tm1Mak/Pecam1⁺ D1.129P2-Pecam1^tm1Mak	increased susceptibility to induced arthritis	J:106275
Pecam1^tm1Mak/Pecam1^tm1Mak B6.129P2-Pecam1^tm1Mak	abnormal cytokine secretion	J:95226
	glomerular capillary congestion	J:95226
	increased vascular permeability	J:95226
	kidney vascular congestion	J:95226
	liver inflammation	J:95226
	liver vascular congestion	J:95226
	pulmonary edema	J:95226
	pulmonary vascular congestion	J:95226
	spleen vascular congestion	J:95226
Pecam1^tm1Mak/Pecam1^tm1Mak D1.129P2-Pecam1^tm1Mak	abnormal leukocyte physiology	J:106275
	increased interferon-gamma secretion	J:106275
	increased susceptibility to induced arthritis	J:106275
	joint inflammation	J:106275
Pecam1^tm1Mak/Pecam1^tm1Mak involves: 129P2/OlaHsd * C57BL/6	abnormal lung morphology	J:110561
	abnormal pulmonary alveolar sac morphology	J:110561
	abnormal pulmonary alveolus wall morphology	J:110561
	decreased lung endothelial cell migration	J:110561
	impaired lung alveolus development	J:110561

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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