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Ncl Gene Detail
Summary
  • Symbol
    Ncl
  • Name
    nucleolin
  • Synonyms
    B530004O11Rik, C23
  • Feature Type
    protein coding gene
  • IDs
    MGI:97286
    NCBI Gene: 17975
  • Gene Overview
    MyGene.info: NCL
  • Alliance
  • Transcription Start Sites
    20 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:86344719-86359400 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 43.94 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    85 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97286
protein coding gene Chr1:86344719-86359455 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016246
protein coding gene Chr1:87598805-87613455 (-)
A/J MGP_AJ_G0016227
protein coding gene Chr1:84354941-84369596 (-)
AKR/J MGP_AKRJ_G0016188
protein coding gene Chr1:86816300-86834362 (-)
BALB/cJ MGP_BALBcJ_G0016184
protein coding gene Chr1:84472588-84488681 (-)
C3H/HeJ MGP_C3HHeJ_G0016012
protein coding gene Chr1:87052919-87067603 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016640
protein coding gene Chr1:90939536-90954212 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014362
protein coding gene Chr1:78849383-78864356 (-)
CAST/EiJ MGP_CASTEiJ_G0015597
protein coding gene Chr1:86299025-86313676 (-)
CBA/J MGP_CBAJ_G0015988
protein coding gene Chr1:93761602-93780329 (-)
DBA/2J MGP_DBA2J_G0016091
protein coding gene Chr1:83663334-83677990 (-)
FVB/NJ MGP_FVBNJ_G0016090
protein coding gene Chr1:82720892-82735622 (-)
LP/J MGP_LPJ_G0016162
protein coding gene Chr1:88703062-88717722 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016116
protein coding gene Chr1:97032697-97048108 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016683
protein coding gene Chr1:86933998-86948663 (-)
PWK/PhJ MGP_PWKPhJ_G0015384
protein coding gene Chr1:82950107-82964932 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015164
protein coding gene Chr1:85891319-85907939 (-)
WSB/EiJ MGP_WSBEiJ_G0015661
protein coding gene Chr1:86578515-86593159 (-)



Homology
more
  • Human Ortholog
    NCL, nucleolin
  • Vertebrate Orthologs
    7
  • Human Ortholog
    NCL, nucleolin
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C23, Nsr1
  • Links
    NCBI Gene ID: 4691
    neXtProt AC: NX_P19338
    UniProt: P19338

  • Chr Location
    2q37.1; chr2:231454748-231464494 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026234 Ensembl Gene Model | MGI Sequence Detail 14682 C57BL/6J ±  kb
transcript ENSMUST00000027438 Ensembl | MGI Sequence Detail 8202 Not Applicable  
polypeptide ENSMUSP00000027438 Ensembl | MGI Sequence Detail 707 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 42
    Genomic 1
    cDNA 36
    Primer pair 5

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-12795, MGD-MRK-12950, MGD-MRK-2398, MGD-MRK-5693, MGI:2442525
References
more
  • Summaries
    All 96
    Developmental Gene Expression 13
    Gene Ontology 25
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:276752 Park YH, et al., Expression of CPNE7 during mouse dentinogenesis. J Mol Histol. 2019 Jun;50(3):179-188

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/12/2020
MGI 6.15
The Jackson Laboratory