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Krt10
Gene Detail
Symbol

Name
ID
Krt10
keratin 10
MGI:96685
Synonyms
cytokeratin 10, D130054E02Rik, K10, K1C1, keratin 10, Krt-1.10, Krt1-10, suprabasal cytokeratin 10
Feature Type
protein coding gene
Genetic Map
Chromosome 11
62.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(12)
Sequence Map
Chr11:99385254-99389364 bp, - strand
From VEGA annotation of GRCm38

  4111 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:137236  Vertebrate Homology Class
1 mouse; 1 western clawed frog

Gene Tree: Krt10

Mutations,
alleles, and
phenotypes
All mutations/alleles(20) : Chemically induced (ENU)(1) Gene trapped(14) Targeted(5)
 
Mutations may result in hyperkeratosis and blistering of the skin.
 
Human Diseases Modeled Using Mouse Krt10 (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(4)
Interactions
Krt10 interacts with 86 markers (Mir19a, Mir19b-1, Mir19b-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (122 records)
Data Summary: Results (184)    Tissues (43)    Images (48)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 17
RNA in situ 159
RT-PCR 8
cDNA source data(132)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(142) Genomic(5) cDNA(135) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000004962 (Evidence)
Ensembl Gene ModelENSMUSG00000019761 (Evidence)
Entrez Gene16661 (Evidence)
UniGene22662
DFCITC1572984, TC1596480, TC1672183
DoTSDT.40149249, DT.91312376
NIA Mouse Gene IndexU033390
Consensus CDS ProjectCCDS25380.1
International Mouse Knockout Project StatusKrt10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004962 VEGA Gene Model | MGI Sequence Detail 4111 C57BL/6J ±  kb
transcript OTTMUST00000011028 VEGA | MGI Sequence Detail 2094 Not Applicable 
polypeptide OTTMUSP00000005149 VEGA | MGI Sequence Detail 561 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(52 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001664 Intermediate filament protein
InterPro IPR018039 Intermediate filament protein, conserved site
InterPro IPR002957 Keratin, type I
Protein Ontology PR:000009451 keratin, type I cytoskeletal 10
References
(Earliest) J:16017 Steinert PM, et al., Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments. Nature. 1983 Apr 28;302(5911):794-800
(Latest) J:210838 Adolphe C, et al., Patched 1 and patched 2 redundancy has a key role in regulating epidermal differentiation. J Invest Dermatol. 2014 Jul;134(7):1981-90
All references(192)
Disease annotation references (1)
Other
accession IDs
MGD-MRK-11630, MGD-MRK-11640, MGI:2441944

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory