Symbol Name ID |
Krt10
keratin 10 MGI:96685 |
Darker colors indicate more annotations |
Human Phenotypes | Palmoplantar hyperkeratosis |
Palmoplantar keratoderma |
Erythroderma |
Abnormal blistering of the skin |
Hyperkeratosis |
Cobblestone-like hyperkeratosis |
Generalized hyperkeratosis |
Congenital nonbullous ichthyosiform erythroderma |
Disease(s) Associated with KRT10 | ||||||||
epidermolytic hyperkeratosis 2 |
Mouse Phenotypes | abnormal sebocyte morphology |
abnormal sebocyte differentiation |
enlarged sebaceous gland |
abnormal sebaceous lipid secretion |
increased sebum secretion |
greasy coat |
ruffled hair |
waved hair |
abnormal skin morphology |
abnormal epidermal layer morphology |
abnormal epidermis stratum basale morphology |
abnormal epidermis stratum corneum morphology |
abnormal stratum corneum lipid matrix formation |
hyperkeratosis |
abnormal epidermis stratum granulosum morphology |
increased keratohyalin granule size |
hypergranulosis |
abnormal epidermis stratum spinosum morphology |
acanthosis |
abnormal epidermis suprabasal layer morphology |
epidermal hyperplasia |
blistering |
flaky skin |
reddish skin |
scaly skin |
skin lesions |
translucent skin |
increased sebocyte proliferation |
decreased skin tensile strength |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||
Krt10tm1Tmm/Krt10tm1Tmm | ||||||||||||||||||||||||||||||
Krt10tm2Tmm/Krt10tm2Tmm | ||||||||||||||||||||||||||||||
Krt10tm1Tmm/Krt10+ | ||||||||||||||||||||||||||||||
Krt10M1Btlr/? | ||||||||||||||||||||||||||||||
Krt10tm1Der/Krt10tm1Der Tg(KRT14-cre/PGR)1Der/0 (conditional) |
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Krt10tm1Der/Krt10+ Tg(KRT14-cre/PGR)1Der/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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