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Kcnc1 Gene Detail
Summary
  • Symbol
    Kcnc1
  • Name
    potassium voltage gated channel, Shaw-related subfamily, member 1
  • Synonyms
    C230009H10Rik, Kcr2-1, KShIIIB, Kv3.1, KV4, NGK2, Shaw
  • Feature Type
    protein coding gene
  • IDs
    MGI:96667
    NCBI Gene: 16502
  • Gene Overview
    MyGene.info: KCNC1
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr7:46396497-46438704 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      42208 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 30.10 cM
  • Mapping Data
    9 experiments
Homology
more
  • Human Ortholog
    KCNC1, potassium voltage-gated channel subfamily C member 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KCNC1, potassium voltage-gated channel subfamily C member 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EPM7, KV3.1, KV4, NGK2
  • Links
    NCBI Gene ID: 3746
    neXtProt AC: NX_P48547
    UniProt: P48547

  • Chr Location
    11p15.1; chr11:17734810-17783055 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from multigenic genotypes
    19 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    24
  • Tissues
    15
  • cDNA Data
    49
  • Literature Summary
    12
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034762 VEGA Gene Model | MGI Sequence Detail 42208 C57BL/6J ±  kb
transcript OTTMUST00000088338 VEGA | MGI Sequence Detail 3156 Not Applicable  
polypeptide OTTMUSP00000048127 VEGA | MGI Sequence Detail 585 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    405 from dbSNP Build 142
  • RFLP
    3
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 53
    cDNA 50
    Primer pair 3

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-11571, MGD-MRK-11580, MGD-MRK-14399, MGI:2443956
References
more
  • Summaries
    All 72
    Developmental Gene Expression 12
    Gene Ontology 9
    Phenotypes 19
  • Earliest
    J:40342 Yokoyama S, et al., Potassium channels from NG108-15 neuroblastoma-glioma hybrid cells. Primary structure and functional expression from cDNAs. FEBS Lett. 1989 Dec 18;259(1):37-42
  • Latest
    J:233469 Vogt D, et al., The parvalbumin/somatostatin ratio is increased in Pten mutant mice and by human PTEN ASD alleles. Cell Rep. 2015 May 12;11(6):944-56
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/10/2017
MGI 6.10 		The Jackson Laboratory