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Il1r2 Gene Detail
Summary
  • Symbol
    Il1r2
  • Name
    interleukin 1 receptor, type II
  • Synonyms
    CD121b, Il1r-2, IL-1 receptor beta chain
  • Feature Type
    protein coding gene
  • IDs
    MGI:96546
    NCBI Gene: 16178
Location & Maps
more
  • Sequence Map
    Chr1:40074079-40125231 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      51153 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 18.65 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    IL1R2, interleukin 1 receptor type 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    IL1R2, interleukin 1 receptor type 2
    Orthology source: HomoloGene
  • Synonyms
    CD121b, CDw121b, IL-1R-2, IL1R2c, IL1RB, IL-1RT2, IL-1RT-2
  • Links
    NCBI Gene ID: 7850
    neXtProt AC: NX_P27930

  • Chr Location
    2q12; chr2:101991816-102028544 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Targeted
    4
  • Genomic Mutations
    1 involving Il1r2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000050443 VEGA Gene Model | MGI Sequence Detail 51153 C57BL/6J ±  kb
transcript OTTMUST00000127995 VEGA | MGI Sequence Detail 1419 Not Applicable  
polypeptide OTTMUSP00000068938 VEGA | MGI Sequence Detail 410 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    373 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
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MGD-MRK-11370, MGD-MRK-11372
References
more
  • Summaries
    All 47
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:14586 Chizzonite R, et al., Two high-affinity interleukin 1 receptors represent separate gene products. Proc Natl Acad Sci U S A. 1989 Oct;86(20):8029-33
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory