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Igha
Gene Detail
Symbol

Name
ID
Igha
immunoglobulin heavy constant alpha
MGI:96444
Synonyms
IgA, Igh-2
Feature Type
gene segment
Genetic Map
Chromosome 12
62.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(19)
Sequence Map
Chr12:113254830-113260236 bp, - strand
From VEGA annotation of GRCm38

  5407 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: immunoglobulin V region
Gene Tree: Igha
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from APF )
 
Homozygous null mice have no detectable levels of IgA, decreased levels of IgG3, and increased levels of most other classes of immunoglobulins.
 
Mutations Annotated to Human Diseases (1)   
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (2)    Tissues (1)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 2
cDNA source data(2)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(37) Genomic(27) cDNA(9) Other(1)
Other database
links
VEGA Gene Model OTTMUSG00000051445 (Evidence)
Ensembl Gene Model ENSMUSG00000095079 (Evidence)
Entrez Gene 238447 (Evidence)
International Mouse Phenotyping Consortium Status Igha
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051445 VEGA Gene Model | MGI Sequence Detail 5407 C57BL/6J ±  kb
transcript OTTMUST00000130060 VEGA | MGI Sequence Detail 2540 Not Applicable 
polypeptide OTTMUSP00000069776 VEGA | MGI Sequence Detail 389 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(2)
Polymorphisms
RFLP(4) : SNPs within 2kb(207 from dbSNP Build 137)    SNPs within 2kb including multiple locations(217)
References
(Earliest) J:12170 Herzenberg LA, et al., Genetics of antibodies. Annu Rev Genet. 1968;2:209-44
(Latest) J:209731 Chopra M, et al., Non-invasive bioluminescence imaging to monitor the immunological control of a plasmablastic lymphoma-like B cell neoplasia after hematopoietic cell transplantation. PLoS One. 2013;8(12):e81320
All references(80)
Other
accession IDs
MGD-MRK-11241

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory