Inactivation of this gene results in female infertility. Additional abnormalities observed in one line of targeted mice include placental defects, growth retardation, loss of the classical heat shock response, and impaired immune response.
|InterPro||IPR000232||Heat shock factor (HSF)-type, DNA-binding|
|InterPro||IPR027072||Heat shock factor protein 1|
|InterPro||IPR027725||Heat shock transcription factor family|
|InterPro||IPR010542||Vertebrate heat shock transcription factor, C-terminal domain|
|InterPro||IPR011991||Winged helix-turn-helix DNA-binding domain|
|Protein Ontology||PR:000008790||heat shock factor protein 1|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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