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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hsf1
heat shock factor 1
MGI:96238
27 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Hsf1tm1Anak/Hsf1tm1Anak
Hsf4tm1Anak/Hsf4tm1Anak
involves: C57BL/6 * CBA * ICR 		cataract J:93301
ruptured lens capsule J:93301
Hsf1tm1Anak/Hsf1tm1Anak
Tg(ACTB-HSF1)1Anak/?
involves: C57BL/6 * CBA * ICR 		abnormal seminiferous tubule morphology J:89846
decreased testis weight J:89846
normal reproductive system phenotype J:89846
Hsf1tm1Ijb/Hsf1tm1Ijb
Tg(TTR-V30M)15Imeg/0
involves: 129S6/SvEvTac * BALB/c * C57BL/6 		abnormal axon morphology J:156658
abnormal digestive system morphology J:156658
abnormal dorsal root ganglion morphology J:156658
abnormal sciatic nerve morphology J:156658
abnormal skin morphology J:156658
abnormal stomach morphology J:156658
increased interleukin-1 beta secretion J:156658
increased tumor necrosis factor secretion J:156658
normal nervous system phenotype J:156658
neurodegeneration J:156658
Hsf1tm1Miv/Hsf1tm1Miv
Hsf2tm1Miv/Hsf2tm1Miv
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		abnormal fertility/fecundity J:88035
abnormal gametogenesis J:88035
abnormal seminiferous tubule morphology J:88035
abnormal testis morphology J:88035
arrest of male meiosis J:88035
azoospermia J:88035
decreased body size J:88035
decreased body weight J:88035
female infertility J:88035
male infertility J:88035
multinucleated giant male germ cells J:88035
prenatal lethality, incomplete penetrance J:88035
small testis J:88035
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory