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Hspa1l Gene Detail
Summary
  • Symbol
    Hspa1l
  • Name
    heat shock protein 1-like
  • Synonyms
    70kDa, Hsc70t, Msh5
  • Feature Type
    protein coding gene
  • IDs
    MGI:96231
    NCBI Gene: 15482
  • Gene Overview
    MyGene.info: HSPA1L
Location & Maps
more
  • Sequence Map
    Chr17:34972703-34979285 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6583 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.51 cM
  • Mapping Data
    11 experiments
Homology
more
  • Human Ortholog
    HSPA1L, heat shock protein family A (Hsp70) member 1 like
  • Vertebrate Orthologs
    12
  • Human Ortholog
    HSPA1L, heat shock protein family A (Hsp70) member 1 like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSP70-1L, HSP70-HOM, HSP70T, hum70t
  • Links
    NCBI Gene ID: 3305
    neXtProt AC: NX_P34931

  • Chr Location
    6p21.3; chr6:31809619-31821999 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    6
  • Gene trapped
    1
  • Targeted
    5
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016296 VEGA Gene Model | MGI Sequence Detail 6583 C57BL/6J ±  kb
transcript OTTMUST00000039162 VEGA | MGI Sequence Detail 2472 Not Applicable  
polypeptide OTTMUSP00000017491 VEGA | MGI Sequence Detail 641 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000008806 heat shock 70 kDa protein 1-like
  • InterPro Domains
    IPR018181 Heat shock protein 70, conserved site
    IPR013126 Heat shock protein 70 family
    IPR029048 Heat shock protein 70kD, C-terminal domain
    IPR029047 Heat shock protein 70kD, peptide-binding domain
Molecular
Reagents
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  • All nucleic 18
    Genomic 8
    cDNA 6
    Primer pair 4

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-10942
References
more
  • Summaries
    All 47
    Developmental Gene Expression 7
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:10291 Matsumoto M, et al., Cloning of a hsp70-related gene expressed in mouse spermatids. Biochem Biophys Res Commun. 1990 Jan 15;166(1):43-9
  • Latest
    J:204898 Akiyama K, et al., A mutation in the nuclear pore complex gene Tmem48 causes gametogenesis defects in skeletal fusions with sterility (sks) mice. J Biol Chem. 2013 Nov 1;288(44):31830-41

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory