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Hoxa7 Gene Detail
Summary
  • Symbol
    Hoxa7
  • Name
    homeobox A7
  • Synonyms
    Hox-1.1
  • Feature Type
    protein coding gene
  • IDs
    MGI:96179
    NCBI Gene: 15404
  • Member of
    Hoxa cluster
  • Gene Overview
    MyGene.info: HOXA7
Location & Maps
more
  • Sequence Map
    Chr6:52214491-52221854 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7364 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 25.40 cM
  • Mapping Data
    11 experiments
Homology
more
  • Human Ortholog
    HOXA7, homeobox A7
  • Vertebrate Orthologs
    12
  • Human Ortholog
    HOXA7, homeobox A7
    Orthology source: HomoloGene
  • Synonyms
    ANTP, HOX1, HOX1.1, HOX1A
  • Links
    NCBI Gene ID: 3204
    neXtProt AC: NX_P31268

  • Chr Location
    7p15.2; chr7:27153716-27156677 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    14 phenotype references
  • All Mutations and Alleles
    6
  • Targeted
    6
  • Genomic Mutations
    1 involving Hoxa7
  • Incidental Mutations
Mice homozygous for a knock-out allele are viable, fertile and grossly normal with no apparent skeletal defects.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018867 VEGA Gene Model | MGI Sequence Detail 7364 C57BL/6J ±  kb
transcript OTTMUST00000141606 VEGA | MGI Sequence Detail 2009 Not Applicable  
polypeptide OTTMUSP00000073977 VEGA | MGI Sequence Detail 229 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    13 from dbSNP Build 142
  • RFLP
Protein
Information
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Molecular
Reagents
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  • All nucleic 67
    Genomic 24
    cDNA 35
    Primer pair 7
    Other 1

    Microarray probesets 4
Other
Accession IDs
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MGD-MRK-10815, MGD-MRK-10880, MGI:2141621
References
more
  • Summaries
    All 103
    Developmental Gene Expression 53
    Gene Ontology 9
    Phenotypes 14
  • Earliest
    J:7833 Colberg-Poley AM, et al., Structural analysis of murine genes containing homoeo box sequences and their expression in embryonal carcinoma cells. Nature. 1985 Apr 25-May 1;314(6013):713-8
  • Latest
    J:226712 Wong SF, et al., Independent regulation of vertebral number and vertebral identity by microRNA-196 paralogs. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4884-93

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory