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Hoxa7 Gene Detail
Summary
  • Symbol
    Hoxa7
  • Name
    homeobox A7
  • Synonyms
    Hox-1.1
  • Feature Type
    protein coding gene
  • IDs
    MGI:96179
    NCBI Gene: 15404
  • Member of
    Hoxa cluster
  • Gene Overview
    MyGene.info: HOXA7
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:52215623-52218573 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 25.40 cM
  • Mapping Data
    11 experiments
Strain
Comparison
more
  • SNPs within 2kb
    10 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96179
protein coding gene Chr6:52214491-52221854 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030746
protein coding gene Chr6:51455699-51463029 (-)
A/J MGP_AJ_G0030715
protein coding gene Chr6:49050333-49057698 (-)
AKR/J MGP_AKRJ_G0030642
protein coding gene Chr6:50756779-50764109 (-)
BALB/cJ MGP_BALBcJ_G0030727
protein coding gene Chr6:49411002-49418349 (-)
C3H/HeJ MGP_C3HHeJ_G0030440
protein coding gene Chr6:50765811-50773168 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031182
protein coding gene Chr6:52591983-52599344 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028388
protein coding gene Chr6:46698147-46705531 (-)
CAST/EiJ MGP_CASTEiJ_G0029843
protein coding gene Chr6:50580763-50588132 (-)
CBA/J MGP_CBAJ_G0030414
protein coding gene Chr6:54789926-54798490 (-)
DBA/2J MGP_DBA2J_G0030564
protein coding gene Chr6:48972764-48980111 (-)
FVB/NJ MGP_FVBNJ_G0030516
protein coding gene Chr6:48583234-48591694 (-)
LP/J MGP_LPJ_G0030649
protein coding gene Chr6:51434382-51441712 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030550
protein coding gene Chr6:57420801-57428136 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031212
protein coding gene Chr6:50685454-50692784 (-)
PWK/PhJ MGP_PWKPhJ_G0029556
protein coding gene Chr6:48596646-48604059 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029390
protein coding gene Chr6:50020857-50028229 (-)
WSB/EiJ MGP_WSBEiJ_G0029920
protein coding gene Chr6:50701595-50708945 (-)



Homology
more
  • Human Ortholog
    HOXA7, homeobox A7
  • Vertebrate Orthologs
    12
  • Human Ortholog
    HOXA7, homeobox A7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ANTP, HOX1, HOX1.1, HOX1A
  • Links
    NCBI Gene ID: 3204
    neXtProt AC: NX_P31268
    UniProt: P31268

  • Chr Location
    7p15.2; chr7:27153716-27156677 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    14 phenotype references
Mice homozygous for a knock-out allele are viable, fertile and grossly normal with no apparent skeletal defects.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 15404 NCBI Gene Model | MGI Sequence Detail 2951 C57BL/6J ±  kb
transcript NM_010455 RefSeq | MGI Sequence Detail 1952 C57BL/6  
polypeptide P02830 UniProt | EBI | MGI Sequence Detail 229 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 71
    Genomic 24
    cDNA 39
    Primer pair 7
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-10815, MGD-MRK-10880, MGI:2141621
References
more
  • Summaries
    All 119
    Developmental Gene Expression 56
    Gene Ontology 10
    Phenotypes 14
  • Earliest
    J:7833 Colberg-Poley AM, et al., Structural analysis of murine genes containing homoeo box sequences and their expression in embryonal carcinoma cells. Nature. 1985 Apr 25-May 1;314(6013):713-8
  • Latest
    J:247259 Naruse C, et al., New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice. FASEB J. 2017 Jun;31(6):2252-2266

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/04/2019
MGI 6.14
The Jackson Laboratory